| Patent Number |
Title Of Patent |
Date Issued |
| 7626040 |
Substituted imidazole compounds as KSP inhibitors |
December 1, 2009 |
| The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses of the compounds. The compounds of the invention have t |
| 7576221 |
Substituted imidazole derivatives |
August 18, 2009 |
| The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention |
| 7553854 |
6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signali |
June 30, 2009 |
| Benzoxazole and benzothiazole compounds and the stereoisomers, tautomers, solvates, oxides, esters, and prodrugs thereof and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic |
| 7470709 |
Benzimidazole quinolinones and uses thereof |
December 30, 2008 |
| Methods of inhibiting various enzymes and treating various conditions are provided that include administering to a subject a compound of Structure I or IB, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds hav |
| 7425557 |
Inhibitors of glycogen synthase kinase 3 |
September 16, 2008 |
| New pyridine-based compounds of Formula I, compositions, and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3-mediated disorders in vivo are provided. The methods, compounds, and compositions of the invention may be employed alon |
| 7423150 |
Substituted benzazoles and methods of their use as inhibitors of Raf kinase |
September 9, 2008 |
| New substituted benzazole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase |
| 7384942 |
Pyrazine based inhibitors of glycogen synthase kinase 3 |
June 10, 2008 |
| New bicyclic based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combinatio |
| 7250443 |
Pyrrole based inhibitors of glycogen synthase kinase 3 |
July 31, 2007 |
| New pyrrole based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination |
| 7071216 |
Substituted benz-azoles and methods of their use as inhibitors of Raf kinase |
July 4, 2006 |
| New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinas |
| 7045519 |
Inhibitors of glycogen synthase kinase 3 |
May 16, 2006 |
| New pyrimidine or pyridine based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone |
| 7037918 |
Inhibitors of glycogen synthase kinase 3 |
May 2, 2006 |
| New pyrimidine or pyridine based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone |
| 6949547 |
Pyrazine based inhibitors of glycogen synthase kinase 3 |
September 27, 2005 |
| New bicyclic based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combinatio |
| 6608063 |
Pyrazine based inhibitors of glycogen synthase kinase 3 |
August 19, 2003 |
| New bicyclic based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combinatio |
| 6489344 |
Inhibitors of glycogen synthase kinase 3 |
December 3, 2002 |
| New pyrimidine or pyridine based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or |
