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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Qiu; Yao-Ling
Address:
Andover, MA
No. of patents:
19
Patents:












Patent Number Title Of Patent Date Issued
8273720 6,11-bicyclolides: bridged biaryl macrolide derivatives September 25, 2012
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compound
8242156 Linked dibenzimidazole derivatives August 14, 2012
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with
8221737 Hepatitis C virus inhibitors July 17, 2012
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with
8188132 Linked dibenzimidazole derivatives May 29, 2012
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with
8163707 4'-allene-substituted nucleoside derivatives April 24, 2012
The present invention discloses compounds of formula (I), or its .beta.-L enantiomer, or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, solvate, prodrug, or combination thereof: ##STR00001## which inhibit, preventing or treating abnormal cellular proliferation and/o
8101643 Benzimidazole derivatives January 24, 2012
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with
7919627 Processes for the preparation of hydroxylamines April 5, 2011
The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT
7622452 C-9 alkenylidine bridged macrolides November 24, 2009
The present invention discloses compounds of formulae (I), (II) or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned
7538225 Processes for the preparation of o-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine May 26, 2009
The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT
7402568 Bicyclic 9a-azalide derivatives July 22, 2008
The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned
7273853 6-11 bicyclic ketolide derivatives September 25, 2007
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compound
7265094 9N-substituted 6-11 bicyclic erythromycin derivatives September 4, 2007
The present invention discloses compounds of formula I, II, III, or IV, or a racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the af
7129221 6,11-bicyclic erythromycin derivatives October 31, 2006
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compound
7064110 6-11 bicycle ketolide derivatives June 20, 2006
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compound
6878691 6-11 bicyclic ketolide derivatives April 12, 2005
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6790835 Bicyclic macrolide derivatives September 14, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6774115 6-O-substituted bicyclic ketolides August 10, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6765016 Bicyclic ketolide derivatives July 20, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6716820 6-O-substituted bicyclic macrolides April 6, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for










 
 
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