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Inventor:
Powell; Robert J.
Address:
Baltimore, MD
No. of patents:
7
Patents:












Patent Number Title Of Patent Date Issued
7393525 Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors July 1, 2008
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said the animal cells with live invasive bacteria, wherein bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic ag
7125718 Method for introducing and expressing genes in animal cells, and bacterial blebs for use in same October 24, 2006
A method for introducing and expressing genes in animal cells, in which the animal cells are transfected with bacterial blebs containing a eukaryotic expression cassette encoding the gene. Bacterial blebs comprising a eukaryotic expression cassette, wherein the bacterial blebs are de
6682729 Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors January 27, 2004
A method for introducing and expressing genes in animal cells is disclosed comprising infecting the animal cells with live invasive bacteria, wherein the bacteria contain a eukaryotic expression cassette encoding the gene. The gene may encode, e.g., a vaccine antigen, a therapeutic agent
6548287 Non-pyrogenic bacterial strains and use of the same April 15, 2003
The present invention provides gram-negative bacterial strains that produce substantially pure non-pyrogenic lipopolysaccharide or lipid A. The present invention also relates to a use of said strains for the preparation of non-pyrogenic DNA and use of the same for introducing endogen
6150170 Method for introducing and expressing genes in animal cells, and live invasive bacterial vectors November 21, 2000
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic
5997881 Method of making non-pyrogenic lipopolysaccharide or A December 7, 1999
The present invention provides gram-negative bacterial strains that produce substantially pure non-pyrogenic lipopolysaccharide or lipid A. The present invention also relates to a use of said strains for the preparation of non-pyrogenic DNA and use of the same for introducing endogen
5877159 Method for introducing and expressing genes in animal cells and live invasive bacterial vectors March 2, 1999
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic










 
 
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