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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Phan; Ly Tam
Address:
Malden, MA
No. of patents:
24
Patents:












Patent Number Title Of Patent Date Issued
7129221 6,11-bicyclic erythromycin derivatives October 31, 2006
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compound
7049417 6,11-4-Carbon bridged ketolides May 23, 2006
Novel 6,11-4-carbon bridged ketolides, pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial inf
6878691 6-11 bicyclic ketolide derivatives April 12, 2005
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6841664 6,11-4-carbon bridged ketolides January 11, 2005
Novel 6,11-4-carbon bridged ketolides, pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for treating bacterial inf
6812216 11-C-substituted derivatives of clarithromycin November 2, 2004
There are described 11-C-substituted derivatives of clarithromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treat
6790835 Bicyclic macrolide derivatives September 14, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6774115 6-O-substituted bicyclic ketolides August 10, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6765016 Bicyclic ketolide derivatives July 20, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6764998 6,11-4C-bicyclic 9a-azalide derivatives July 20, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6753415 23-O-substituted 5-O-mycaminosyltylonide derivatives June 22, 2004
There are described novel 5-O-mycaminosyltylonide (OMT) analogs possessing increased antibacterial activity toward Gram positive and Gram negative bacteria as well as macrolide resistant Gram positives and pharmaceutically acceptable compositions comprising a therapeutically effectiv
6753318 6,11-4-carbon bridged erythromycin derivatives June 22, 2004
Novel 6,11-4-carbon bridged erythromycin derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are methods for treat
6750204 11-C-substituted ketolides June 15, 2004
There are described 11-C-substituted derivatives of erythromycin and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treatin
6727229 11,12-substituted lactone ketolide derivatives having antibacterial activity April 27, 2004
Novel 11-12 substituted lactone ketolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for trea
6720308 Anhydrolide derivatives having antibacterial activity April 13, 2004
Novel 11-12 substituted lactone anhydrolide derivatives and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically-acceptable carrier are described. Also described are a method for t
6716820 6-O-substituted bicyclic macrolides April 6, 2004
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6710034 5-O-mycaminosyltylonide derivatives March 23, 2004
There are described novel 5-O-mycaminosyltylonide derivatives and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treating
6680299 4'-substituted leucomycins January 20, 2004
There are described novel 4' substituted 16-membered macrolides and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described are a method for treatin
6667338 9-amino erythromycin derivatives with antibacterial activity December 23, 2003
Compounds of formula (I) ##STR1##and formula (II) ##STR2##or therapeutically acceptable salts or prodrugs thereof are useful as antibacterial agents. Methods to make the compounds, compositions containing the compounds, and methods of treatment using the compounds are also disclo
6664240 Tylosin derivatives having antibacterial activity December 16, 2003
There are described novel substituted tylosin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacterial
6645941 6,11-3C-bicyclic 9a-azalide derivatives November 11, 2003
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR1##which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for
6576615 4'-O-substituted tylosin analogs June 10, 2003
There are described novel 4' substituted tylosin analogs and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier. Also described is a method for treating bacter
6569836 6-O-alkyl-2-nor-2-substituted ketolide derivatives May 27, 2003
The present invention relates to 6-O-alkyl-2-nor-2-substituted ketolide compound or a derivative thereof, a composition comprising the compound and a suitable carrier, a method of preparing the compound, and a method of treatment and prevention of in mammals comprising administering said
6462026 Bicyclic leucomycins October 8, 2002
Bicyclic leucomycins and pharmaceutically acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmace
6436906 9-amino-14-membered macrolides derived from leucomycins August 20, 2002
Novel 9-amino-14-membered macrolides and pharmaceutically-acceptable compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a m










 
 
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