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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Pfefferle; Walter
Address:
Halle, DE
No. of patents:
73
Patents:


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Patent Number Title Of Patent Date Issued
8048665 Nucleotide sequences encoding alanine racemase from coryneform November 1, 2011
The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the alr gene, and a host-vector system having a coryneform host bacterium in which the alr gene is present in attenuated form and a vector which carries at least the alr gene accordin
7981640 L-lysine-producing corynebacteria and process for the preparation of L-lysine July 19, 2011
L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihydrodipico
7524657 Alleles of the sigA gene from coryneform bacteria April 28, 2009
The invention relates to alleles of the sigA gene from coryneform bacteria which code for sigma factors A and a process for the fermentative preparation of L-lysine using bacteria which contain these alleles.
7435584 L-lysine-producing corynebacteria and process for the preparation of L-lysine October 14, 2008
The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the
7416863 Nucleotide sequences for encoding of the lysR2-gene August 26, 2008
Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleo
7348037 Sulfur-containing animal-feed additives March 25, 2008
The invention relates to sulfur-containing animal-feed additives produced from fermentation liquors, and to processes for their production.
7306939 Nucleotide sequences encoding the gpm gene December 11, 2007
The invention provides nucleotide sequences of the gpm gene which encode phosphoglycerate mutase, and fermentation processes for the preparation of amino acids, especially L-lysine, using corynebacteria wherein the gpm gene is amplified.
7262036 Process for the preparation of l-amino acids August 28, 2007
Disclosed herein is an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID N
7252977 Nucleotide sequences which code for the msiK gene August 7, 2007
The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which encodes the sugar import protein K (msiK) gene, and a host-vector system having a coryneform host bacterium in which the msiK gene is present in enhanced form an
7205144 Nucleotide sequences encoding a sensor kinase, citA, from Corynebacterium glutamicum April 17, 2007
The invention related to an isolated nucleic acid consisting of a fragment of the polynucleotide of Corynebacterium glutamicum citA gene or a fragment of the full complement of the polynucleotide of the C. glutamicum citA gene wherein said fragment is at least 30 consecutive nucleoti
7205131 Process for the preparation of L-amino acids via overexpression of the PTSH gene April 17, 2007
The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polyn
7160703 Nucleotide sequences coding for the PtsI protein January 9, 2007
The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which the ptsI gene is enhanced.
7144724 Process for the production of L-amino acids by fermentation using coryneform bacteria December 5, 2006
A process for the production of an L-amino acid wherein coryneform bacteria (e.g. Coryneform glutamicum) in which expression of the mqo gene coding for malate quinone oxidoreductase is attenuated are fermented to produce a desired amino acid, and the amino acid is concentrated in the
7132272 Nucleotide sequence encoding corynebacterium glutamicum leucine response regulatory protein November 7, 2006
The present invention relates to an isolated polynucleotide coding for the lrp gene and to a process for the fermentative production of L-amino acids by altering the expression of this gene.
7129066 Nucleotide sequences coding for the citE gene October 31, 2006
The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide that is at least 70% identical with a polynucleotide that codes for a polypeptide containing the amino acid sequence of SEQ ID No. 2, b) polynucleotide
7118904 Nucleotide sequences which code for the eno gene October 10, 2006
The present invention is directed to nucleotide sequences coding for a bacterial enolase enzyme. These sequences may be used in improved methods for the fermentative preparation of amino acids using coryneform bacteria.
7094584 L-Lysine-producing corynebacteria and process for the preparation of L-lysine August 22, 2006
The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the
7078502 Nucleotide sequences for encoding of the lysR2-gene July 18, 2006
Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleo
7074607 Polynucleotide sequences which encode the zwa1 gene July 11, 2006
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of
7049106 Process for the production of L-amino acids by fermentation using coryneform bacteria with an at May 23, 2006
A process for the production of an L-amino acid wherein coryneform bacteria (e.g. Coryneform glutamicum) in which expression of the mqo gene coding for malate quinone oxidoreductase is attenuated are fermented to produce a desired amino acid, and the amino acid is concentrated in the
7038034 Nucleotide sequences coding for the Dep33 efflux protein May 2, 2006
The invention provides nucleotide sequences from Coryneform bacteria coding for the dep33 efflux protein and a process for the fermentative preparation of amino acids using bacteria in which the dep33 efflux protein is attenuated.
7037689 Methods for producing amino acids in coryneform bacteria using an enhanced sigC gene May 2, 2006
The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the sigC gene from Corynebacterium glutamicum, and a host-vector system having a coryneform host bacterium, such as Corynebacterium glutamicum, and a vector which carries at least the
7026158 Nucleotide sequences which code for the mikE17 gene April 11, 2006
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of
6995000 Nucleotide sequences coding for the sigM gene February 7, 2006
The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which encodes the sigma factor M (sigM) gene, and a host-vector system having a coryneform host bacterium in which the sigM gene is present in enhanced form and a vector
6987015 Nucleotide sequences encoding the pfkA gene January 17, 2006
An isolated polynucleotide containing a polynucleotide sequence selected from the following group: a) a polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID NO:2, b) a polynucleotide which encodes
6972190 Nucleotide sequences which code for the cstA gene December 6, 2005
The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which codes for the carbon starvation protein A (cstA) gene, and a host-vector system having a coryneform host bacterium in which the cstA gene is present in enhanced
6958228 Nucleotide sequence which code for the metH gene October 25, 2005
An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide that codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which
6949374 FadD15 gene of Corynebacterium glutamicum, encoding an acyl-CoA synthase polypeptide September 27, 2005
The invention relates to a genetically modified coryneform bacterium, the fadD15 gene of which is amplified, and an isolated polynucleotide which codes for acyl-CoA synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification o
6942996 Isolated polynucleotide from Corynebacterium encoding a homocysteine methyltransferase September 13, 2005
An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide that codes for a polypeptide which comprises the amino acid sequence of SEQ ID. No. 2, b) polynucleotide which
6939695 Nucleotide sequences which code for the rpsL gene September 6, 2005
An isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polyn
6913910 Nucleotide sequences coding for the glk-gene July 5, 2005
The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising: a) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contains the amino acid sequence of SEQ ID No. 2, b) polynucle
6913908 Methods of making L-amino acids in coryneform using the sigE gene July 5, 2005
The present invention relates lo an isolated polynucleotide from Corynebacterium glutamicum comprising a polynucleotide sequence chosen from the group c insisting of (a) a polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptid
6902916 Nucleotide sequences coding for the 1ysR1 gene June 7, 2005
The present invention relates to polynucleotides corresponding to the lysR1 gene and which encode a LysR1 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR1 transcriptional regulator activity.
6897055 Nucleotide sequences coding for the genes sucC and sucD May 24, 2005
The invention relates to polynucleotides that contain polynucleotide sequences coding for the genes sucC and sucD, selected from the group a) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contains the amino acid sequence of SEQ ID No. 2,
6890744 Methods for producing amino acids in coryneform bacteria using an enhanced sigD gene May 10, 2005
The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which codes for the sigD gene, and a host-vector system having a coryneform host bacterium in which the sigD gene is present in enhanced form and a vector which carries at
6861246 L-lysine-producing corynebacteria and process for the preparation of lysine March 1, 2005
The invention relates to L-lysine-producing strains of corynebacteria with enhanced pyc gene (pyruvate carboxylase gene), in which strains additional genes, chosen from the group consisting of the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), t
6830921 Nucleotide sequences which code for the ACP gene December 14, 2004
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70 % to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of
6825030 Nucleotide sequences encoding a sensor kinase, citA, from corynebacterium glutamicum November 30, 2004
The present invention is related to nucleotide sequences encoding a sensor kinse, citA, from Corynebacterium glutamicum.
6822085 Nucleotide sequences which code for the cysD, cysN, cysK, cysE and cysH genes November 23, 2004
Nucleotide sequences from coryneform bacteria which code for the cysD, cysN, cysK, cysE and cysH genes and a process for the fermentative preparation of amino acids using bacteria in which the genes mentioned are enhanced, a process for the fermentative preparation of L-amino acids u
6818432 Nucleotide sequences encoding the ptsH gene November 16, 2004
The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) pol
6815196 Nucleotide sequences encoding o-succinylhomoserine sulfhydrylase November 9, 2004
The present invention relates to isolated polynucleotides from Corynebacterium glutamicum encoding proteins of the transcription activator (MetR) and O-succinylhomoserine sulfhydrylase (MetZ). The invention also relates to producing L-amino acids, particularly methionine, in corynefo
6812016 Nucleotide sequences which code for the metY gene November 2, 2004
The present invention relates to isolated polynucleotides which encode proteins with O-acetylhomoserine sulfhydrylase, vectors and cells containing the polynucleotides as well as methods of preparing L-amino acids.
6806068 Nucleotide sequences which encode the pfk gene October 19, 2004
The present invention is directed to nucleotide sequences coding for phosphofructokinase which have been derived from Corynebacterium glutamicum. The invention also encompasses methods for fermentatively producing amino acids using bacteria in which phosphofructokinase activity has b
6783967 Nucleotide sequences which code for the rpoB gene August 31, 2004
The present invention relates to polynucleotides corresponding to the rpoB gene and which encode the .beta.-subunit of RNA polymerase B, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having activity of the .beta.-subunit of RNA
6777206 Nucleotide sequences which code for the RodA protein August 17, 2004
The invention provides nucleotide sequences from Coryneform bacteria which code for the RodA protein and a process for the fermentative preparation of amino acids using bacteria in which the rodA gene is enhanced.
6759224 Nucleotide sequences which code for the sahH gene July 6, 2004
An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of a) polynucleotide which is at least 70% identical to a polynucleotide that codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which
6759218 Nucleotide sequences coding for the glbO gene July 6, 2004
The present invention provides an isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucl
6746855 L-lysine-producing corynebacteria and process for the preparation of L-lysine June 8, 2004
The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the
6746854 Nucleotide sequences encoding histidine kinase from corynebacterium glutamicum June 8, 2004
This invention relates to novel polynucleotide sequences encoding the histidine kinase luminescence expression sensor (luxS) gene from Corynebaclerium glutamicum, probes to the novel polynucleotide sequences encoding the luxS gene, vector and host cells containing the novel luxS poly
6740742 Nucleotide sequences encoding the dapC gene and process for the production of L-lysine May 25, 2004
The invention relates to an isolated polynucleotide from coryneform bacteria wherein the polynucleotide encodes a protein having n-succinylaminokeptopimelate transaminase activity.
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