| Patent Number |
Title Of Patent |
Date Issued |
| 7553453 |
Assay implementation in a microfluidic format |
June 30, 2009 |
| An assay implementation in a microfluidic format in a cartridge relating to a point-of-care instrument platform for monitoring and diagnosing infectious diseases (e.g., AIDS and malaria). The platform may also provide a complete blood count. The instrument platform may hold the cartr |
| 7485153 |
Fluid free interface for a fluidic analyzer |
February 3, 2009 |
| Instrument-cartridge interfaces for fluidic analyzers that have an instrument and a removable cartridge are disclosed. For example, and in one illustrative embodiment, the instrument may include a needle that is adapted to penetrate a septum on a removable cartridge. In another illus |
| 7471394 |
Optical detection system with polarizing beamsplitter |
December 30, 2008 |
| An optical detection system for use in flow cytometry or the like, which includes a polarizing beamsplitter 820 such as a Wollaston prism. A light source provides an input light beam to a flow stream, wherein the input light beam has a polarization direction. The particles in the flow st |
| 7333197 |
Raman detection based flow cytometer |
February 19, 2008 |
| A method and apparatus for enabling chemical identification of individual particles, cells of molecules by obtaining a Raman spectrum of a particle, cell or molecule as it flows past a sensing point in a flow cytometer. The particles, which may be cells or molecules, are associated w |
| 7331224 |
Tilt-insensitive flow sensor |
February 19, 2008 |
| A flow sensor is provided having a substrate with a sensing element and flow channel over the sensing element. The sensing element senses at least one property of a fluid. The flow channel is configured such that tilting the flow sensor does not have a significant effect on the measu |
| 7312870 |
Optical alignment detection system |
December 25, 2007 |
| An optical alignment detection system for detecting the alignment of a first object relative to a second object is provided. One or more light sources and one or more light detectors, either or both of which are secured relative to the second object, are used to detect the position of |
| 7277166 |
Cytometer analysis cartridge optical configuration |
October 2, 2007 |
| A medium having microfluidic circuitry for sampling and analyses. The medium may be a cartridge having a window countersunk into it and containing a flow channel. The flow channel may have items of interest flowing through it. Analyses of these items may be optical involving one or m |
| 7258003 |
Flow sensor with self-aligned flow channel |
August 21, 2007 |
| A flow sensor is provided having a substrate with a sensing element and flow channel aligned over the sensing element. The sensing element senses at least one property of a fluid. The flow channel is aligned by one or more guide elements formed in an alignment layer. The flow channel acr |
| 7255001 |
Thermal fluid flow sensor and method of forming same technical field |
August 14, 2007 |
| A thermal fluid flow sensor and method of forming same. The flow sensor has an integrated circuit substrate, such as a silicon substrate, and a region of low thermal conductivity material carried on the top surface of the integrated circuit substrate. One or more pairs of temperature |
| 7215425 |
Optical alignment for flow cytometry |
May 8, 2007 |
| An optical alignment system for aligning a light beam with a core flow in a flow stream. The flow stream may have a sheath fluid and a core flow, where the core flow has a current position within the flow stream. A light source may be used to produce a light beam, and an optical element |
| 7130046 |
Data frame selection for cytometer analysis |
October 31, 2006 |
| A system for detecting when a core stream in a channel of a flow device is adequate for sufficient data accession. The system may determine the time period from the beginning of a sample run in a channel of a flow device to when the core stream is adequate. Data of detected FALS versus S |
| 7109842 |
Robust fluid flow and property microsensor made of optimal material |
September 19, 2006 |
| A robust sensor that incorporates the necessary physical structure and thermal characteristics is capable of measuring fluid flow and properties under harsh environmental conditions. The sensor die is made of a material with thermal conductivity tailored to provide the thermal transm |
| 7096125 |
Architectures of sensor networks for biological and chemical agent detection and identification |
August 22, 2006 |
| A sensor network provides the ability to detect, classify and identify a diverse range of agents over a large area, such as a geographical region or building. The network possesses speed of detection, sensitivity, and specificity for the diverse range of agents. Different functional leve |
| 7016022 |
Dual use detectors for flow cytometry |
March 21, 2006 |
| An optical alignment system for aligning a light beam with a core flow in a flow stream. The flow stream may have a sheath fluid and a core flow, where the core flow has a current position within the flow stream. A light source may be used to produce a light beam, and an optical element |
| 7000330 |
Method and apparatus for receiving a removable media member |
February 21, 2006 |
| The present invention is directed towards receiving removable media, and in some embodiments, providing tighter alignment tolerances between an inserted removable media member and a receiving device. The present invention is also directed towards providing one or more electrical or o |
| 6991847 |
Light emitting photonic crystals |
January 31, 2006 |
| The invention relates to processes for the synthesis of 2-D and 3-D periodic porous silicon structures and composites with improved properties having the advantages of porous silicon and photonic bandgap materials. Photonic crystals comprise a two dimensionally periodic or three dime |
| 6970245 |
Optical alignment detection system |
November 29, 2005 |
| An optical alignment detection system for detecting the alignment of a first object relative to a second object is provided. One or more light sources and one or more light detectors, either or both of which are secured relative to the second object, are used to detect the position of |
| 6794981 |
Integratable-fluid flow and property microsensor assembly |
September 21, 2004 |
| An integratable fluid flow and property microsensor assembly is configured to be operably embedded in a microfluidic cartridge of the type used in lab-on-a-chip systems. The assembly is a robust package having a microstructure flow sensor contained within a housing in order to achieve |
| 6721476 |
Optical demultiplexer based on three-dimensionally periodic photonic crystals |
April 13, 2004 |
| The invention provides photonic crystal optical demultiplexer devices produced from a three-dimensionally-periodic, porous, dielectric, photonic crystalline structure, which has surfaces or interfaces that are inverse replicas of the surfaces of a monodispersed sphere array. Such a photo |
| 6597438 |
Portable flow cytometry |
July 22, 2003 |
| A portable or wearable cytometer that can be used at remote locations, such as in the field or at home. The flow cytometer of the present invention may help improve the healthcare of many weak, sick or elderly people by providing early detection of infection. By detecting the infection e |
| 6549275 |
Optical detection system for flow cytometry |
April 15, 2003 |
| An optical detection system for flow cytometry that uses two or more light sources positioned laterally at different distances from the central axis of the flow stream for providing light through different parts of the flow stream. By using two or more light sources, the particle positio |
| 6322247 |
Microsensor housing |
November 27, 2001 |
| A microsensor housing having a structure with at least one inlet at one end and a thermal property sensor at the other end. Situated between the inlet and the sensor is a convection shield. Sampled fluid is taken in the inlet from a channel carrying the fluid to be sampled. The convectio |
| 6184773 |
Rugged fluid flow and property microsensor |
February 6, 2001 |
| A thermal fluid flow or property sensor having no exposed contact wires or contact pads in the fluid flow path to obstruct measurements, flat fully passivated sensor surfaces and high corrosion resistance is implemented over a honeycombed thermal isolation chamber. |
