| Patent Number |
Title Of Patent |
Date Issued |
| 6896659 |
Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragilit |
May 24, 2005 |
| A method is provided for site specific delivering therapeutic or diagnostic agents to a region in a fluid-filled cavity, vessel or tissue using an agent-loaded microbubble population. The population has controlled fragility characterized by a uniform wall thickness to diameter ratio |
| 6776761 |
Hollow microspheres with controlled fragility for medical use |
August 17, 2004 |
| A composition for ultrasonic imaging is described having a microbubble population of controlled fragility. The microbubbles comprise an outer shell and a hollow core. The ratio of shell thickness to microbubble diameter is substantially similar across the population of microbubbles. A |
| 6524608 |
Intravesical drug delivery system |
February 25, 2003 |
| Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provided sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bi |
| 6482518 |
Excipient for the lyophilization of aqueous suspensions of microparticles |
November 19, 2002 |
| An excipient for lyophilizing a suspension of microparticles is provided comprising an oil-in-water emulsion of an aqueous phase and an organic phase where the organic phase has a freezing point of about or higher than the freezing point of the aqueous phase. When frozen and dried with a |
| 6207180 |
Intravesical drug delivery |
March 27, 2001 |
| Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provide sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bio |
| 6193951 |
Microparticles useful as ultrasonic contrast agents |
February 27, 2001 |
| Microparticles are provided comprising a shell of an outer layer of a biologically compatible material and an inner layer of biodegradable polymer. The core of the microparticles contain a gas, liquid or solid for use in drug delivery or as a contrast agent for ultrasonic contrast im |
| 6039967 |
Intravesical drug delivery system |
March 21, 2000 |
| Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provide sustained release of drugs. Configurations are provided which are insertable through a catheter, such as a coiled filament, patch or a flowable gel. The device is bio |
| 5977171 |
Sustained release emulsions |
November 2, 1999 |
| Ophthalmic methods and compositions are disclosed where particles of the dispersed phase of emulsions are themselves dispersed and stably maintained in physical separation by lightly crosslinked, water swellable polymers present in an aqueous polymeric system formulated for administr |
| 5977044 |
Liquid peracid precursor colloidal dispersions: macroemulsions |
November 2, 1999 |
| A stable liquid peracid precursor composition for delivering a bleaching and cleaning material is provided in which the liquid peracid precursor composition combines a dispersion medium which comprises a stabilizing effective amount of a liquid matrix and an emulsifier, and a dispersed |
| 5837226 |
Ocular microsphere delivery system |
November 17, 1998 |
| A sustained release drug delivery composition and a method of making same are provided which comprises microspheres containing a pharmaceutically active agent, a core of a ion-exchange resin and a polymeric coating completely surrounding the core wherein the coating is water-insoluble an |
| 5776877 |
Liquid peracid precursor colloidal dispersions: macroemulsions |
July 7, 1998 |
| A stable liquid peracid precursor composition for delivering a bleaching and cleaning material is provided in which the liquid peracid precursor composition combines a dispersion medium which comprises a stabilizing effective amount of a liquid matrix and an emulsifier, and a dispersed |
| 5767153 |
Sustained release emulsions |
June 16, 1998 |
| Ophthalmic methods and compositions are disclosed where particles of the dispersed phase of emulsions are themselves dispersed and stably maintained in physical separation by lightly crosslinked, water swellable polymers present in an aqueous polymeric system formulated for administr |
| 5731005 |
Hydrogel-based microsphere drug delivery systems |
March 24, 1998 |
| The present invention provides a sustained-release delivery composition for ophthalmic drugs comprising cross-linked hydrogel microspheres having a binding affinity for the drug. |
| 5710296 |
Process for preparing phenyl esters |
January 20, 1998 |
| A method for preparing phenyl esters in high yields under mild reaction conditions is provided. Particularly preferred phenyl esters prepared in accordance with the inventive method are alkanyloxy-benzene compounds having a C.sub.2-18 alkyl. The method is practiced by reacting a carb |
| 5667735 |
Opthalmic mold coatings |
September 16, 1997 |
| A method is provided for applying a coating to an ophthalmic device by applying a coating to a face of the mold used to make the device and partially curing the coating, or, if the viscosity is sufficiently high, leaving the coating uncured. Then the liquid used to form the lens is p |
| 5551663 |
Plastic molds for ophthalmic devices and methods for forming same |
September 3, 1996 |
| Plastic molds for ophthalmic devices and methods of making such molds are disclosed. The plastic molds are provided with abrasion resistant, release-enhancing faces formed by coatings of particular compositions of polyacryloylated alkane polyols and alkane polyols. |
| 5459176 |
Radiation curable coating for plastic articles |
October 17, 1995 |
| Abrasion resistant, radiation curable compositions are provided for forming coatings over plastic substrates. Such compositions are particularly provided for forming an abrasion resistant, tintable coating over polycarbonate ophthalmic lenses. Generally, the radiation-curable coating |
| 5415796 |
Liquid nonaqueous detergent with stable, solubilized peracid |
May 16, 1995 |
| The invention provides a stable, liquid, substantially nonaqueous detergent comprising:at least one imidoperacid with the structure ##STR1## wherein R is C.sub.1-20 alkylene, R.sup.1 and R.sup.2 are individually H or C.sub.1-6 alkyl or alkenyl, or R.sup.1 and R.sup.2 join to form a |
| 5269962 |
Oxidant composition containing stable bleach activator granules |
December 14, 1993 |
| The present invention provides stable bleach activator granules comprising:(a) a peroxygen bleach activator having the structure: ##STR1## wherein R is C.sub.1-20 branched or straight chain alkyl, alkoxylated alkyl, cycloalkyl, alkenyl, aryl, substituted aryl, alkylaryl; R' and R" ar |
