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Inventor:
Nique; Francois
Address:
Le Perreux sur Marne, FR
No. of patents:
16
Patents:












Patent Number Title Of Patent Date Issued
8168667 Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such May 1, 2012
Compounds of formula (I): ##STR00001## wherein X is O or S, R.sub.1 is acyl, aldehyde, cycloalkyl, an optionally substituted alkyl, alkenyl or alkynyl, R.sub.2 is H, alkyl, hydroxyalkyl, haloalkyl, alkenyl, or alkynyl; substituted alkyl; alkylcarbonyl; R.sub.3 and R.sub.4 are H, ha
7968581 Imidazolidine compounds as androgen receptor modulators June 28, 2011
Novel compounds are disclosed that have a Formula represented by the following: ##STR00001## wherein X, R.sup.1, R.sup.2a, R.sup.2b, R.sup.2c, R.sup.3a R.sup.3b, R.sup.4a, R.sup.4b, R.sup.4c, and m1 are as described herein. The compounds may be prepared as pharmaceutical compositio
6566542 17-Halogenated 19-nor steroids, preparation process and intermediates, use as medicaments and th May 20, 2003
A process for the preparation of a compound of the formula ##STR1##wherein the substituents are defined as in the specification.
6541464 Steroids substituted at the 11-position, process for their preparation, their use as medicament April 1, 2003
Compounds of the formula ##STR1##Where the substituents are defined in the application.
6482813 Steroids substituted at the 11-position, process for their preparation, their use as medicament November 19, 2002
Compounds of formula ##STR1##for treating osteoporosis with minimal estrogenic activity are disclosed.
6462211 4-halogenated steroids, their preparation process and intermediates, their use as medicaments an October 8, 2002
A subject of the invention is the compounds of formula (I): ##STR1##in which X is a halogen atom, D represents the remainder of an optionally substituted pentagonal or hexagonal ring and optionally carrying an unsaturation, R.sub.1, R.sub.2, R.sub.3, R.sub.4, Y and n are as defined i
6423700 17-halogenated 19-nor steroids, method and intermediates for preparing same, use as medicines an July 23, 2002
A compound of the formula ##STR1##wherein the substituents are as defined in the application and its non-toxic, pharmaceutically acceptable acid and base salts useful for hormone replacement for treating menopause or perimenopause without activity at the uterine level treating osteop
6399766 4-halogenated steroids, their preparation process and intermediates, their use as medicaments an June 4, 2002
A subject of the invention is the compounds of formula (I): ##STR1##in which X is a halogen atom, D represents the remainder of an optionally substituted pentagonal or hexagonal ring and optionally carrying an unsaturation, R.sub.1, R.sub.2, R.sub.3, R.sub.4, Y and n are as defined i
6239121 4- Halogenated steroids, preparation method and intermediates, application as medicines and phar May 29, 2001
A subject of the invention is the compounds of formula (I): ##STR1##in which X is a halogen atom, D represents the remainder of an optionally substituted pentagonal or hexagonal ring and optionally carrying an unsaturation, R.sub.1, R.sub.2, R.sub.3, R.sub.4, Y and n are as defined i
6207657 Steroids substituted in position 11, method of preparation, application as medicines and pharmac March 27, 2001
The invention concerns steroid compounds of general formula (I) in which n=2, 3, either R.sub.1 and R.sub.2.dbd.H, (C.sub.1 -C.sub.4) alkyl, or R.sub.1 and R.sub.2 form with nitrogen a heterocyclic compound, X.dbd.OH optionally esterified, Y.dbd.(C.sub.1 -C.sub.4)alkyl, and their additiv
6011026 Method of treating menopause or perimenopause January 4, 2000
A method of treating menopause or perimenopause without estrogenic activity at the uterine level in women comprising administering to women an amount of a steroid of the formula ##STR1## wherein the substituents are defined as in the specification sufficient to treat menopause or
6005003 Derivatives of dihydro or tetrahydronaphthalene, and the pharmaceutical compositions containing December 21, 1999
A subject of the invention is the compounds of general formula (I): ##STR1## in which R1=H, alkyl, acyl, R2 and R3=H, alkyl, R4=aryl, heteroaryl, X=O, CH2, Y=OH, O-alkyl or NRaRb, as well as the salts, their preparation processes, the intermediates of these processes, their use as me
5981516 Method of treating menopause or perimenopause November 9, 1999
A method of treating cholesterol without estrogenic activity at the uterine level in women comprising administering to women an amount of a steroid of the formula ##STR1## wherein the substituents are defined as in the specification without estrogenic activity at the uterine leve
5705494 Anti-estrogenic activity of II.beta.-substituted-19-NOR Steroids January 6, 1998
Disclosed is a method of inducing anti-estrogenic activity in warm-blooded animals by the administration of a compound of the formula ##STR1## wherein the substituents are as defined in the specification.
5679788 11 beta-substituted-19 nor-steroids October 21, 1997
Intermediate compounds of a formula selected from the group consisting of ##STR1## which are useful intermediates for the preparation of final products of the formula ##STR2## wherein the substituents are defined in the specification.
5494907 11-.beta. substituted-19-nor steroids February 27, 1996
A compound selected from the group consisting of a compound of the formula ##STR1## wherein the substituents are defined as in the specification having anti-estrogen activity.










 
 
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