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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Needham; David
Address:
Durham, NC
No. of patents:
7
Patents:




Patent Number Title Of Patent Date Issued
6726925 Temperature-sensitive liposomal formulation April 27, 2004
A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the primary lipid source for the lipid bilayer membrane and the surface active agent is contained in the bilayer membrane in an amo
6296870 Liposomes containing active agents October 2, 2001
Liposomes formulations are designed to maximize the amount of poorly water-soluble active agent that can be carried by the liposome. Liposomes containing active agent in the lipid bilayer of the liposome, and/or entrapped within the liposome interior space in a micellar preparation are
6210611 Methods for producing gas microbubbles having lipid-containing shells formed thereon April 3, 2001
A method for producing a gas microbubble comprises subjecting the gas microbubble to isothermal conditions or cooling conditions such that the lipid-containing shell cools at a rate ranging from about 10.sup.0.degree. C./min. to about 10.sup.3.degree. C./min., and wherein said subjecting
6200598 Temperature-sensitive liposomal formulation March 13, 2001
Temperature sensitive liposomes containing active agents are described. The liposomes comprise phospholipids and a surface active agent, such as a lysolipid, that increases the amount of active agent released by the liposome at the phase transition temperature of the liposome. Such l
6143321 Liposomes containing active agents November 7, 2000
Liposomes formulations are designed to maximize the amount of poorly water-soluble active agent that can be carried by the liposome. Liposomes containing active agent in the lipid bilayer of the liposome, and/or entrapped within the liposome interior space in a micellar preparation are
5882679 Liposomes containing active agents aggregated with lipid surfactants March 16, 1999
Liposomes contain active agents which are aggregated with a lipid surfactant. The composition of the liposome membrane stabilizes the membrane against the disruptive effects of the active agent-surfactant aggregate contained therein.
5827533 Liposomes containing active agents aggregated with lipid surfactants October 27, 1998
Liposomes contain active agents which are aggregated with a lipid surfactant. The composition of the liposome membrane stabilizes the membrane against the disruptive effects of the active agent-surfactant aggregate contained therein.


 
 
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