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Inventor: Michel; Karl H.
Address: Indianapolis, IN
No. of patents: 32
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| 5571901 |
Insecticide and miticide compositions containing A83543 compounds |
November 5, 1996 |
| Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A83543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salts |
| 5496931 |
Insecticide and miticide A83543 compounds and their method of production by fermentation |
March 5, 1996 |
| Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A983543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salt |
| 5362634 |
Process for producing A83543 compounds |
November 8, 1994 |
| Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A983543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salt |
| 5286648 |
A84575 antibiotics |
February 15, 1994 |
| Newly discovered lipoglycopeptide antibiotic A84575 complex, comprising factors A, B, C, D, E, F, G, and H, is produced by submerged aerobic fermentation of a culture selected from Streptosporangeum carneum NRRL 18437, Streptosporangeum carneum NRRL 18505 or an A84575-producing mutant |
| 5286631 |
Process for producing the A10255 complex and corresponding microorganism |
February 15, 1994 |
| Newly-discovered antibiotic A10255 factors B, C, E, and F are produced by submerged aerobic fermentation of previously-unknown Streptomyces gardneri strain NRRL 15922, or an A10255-producing variant, mutant or recombinant thereof. The antibiotics are active against a wide variety of path |
| 5239064 |
A59770 antibiotics |
August 24, 1993 |
| A novel antibiotic complex, A59770, individual factors and derivatives thereof, are provided. The A59770 compounds are useful as pesticides, particularly as rodenticides. Further provided are methods for reducing a rodent population, rodenticidal compositions, and an A59770-producing |
| 5229362 |
Antibiotic A10255 complex and factors, and process and production therefor |
July 20, 1993 |
| Newly-discovered antibiotic A10255 factors B, C, E, F, G, H, and J are produced by submerged aerobic fermentation of Streptomyces gardneri NRRL 15537 and NRRL 18260 or an A10255-producing variant or mutant thereof. The antibiotics are active against a wide variety of pathogenic bacteria, |
| 4880735 |
Process for producing antibiotic A47934 |
November 14, 1989 |
| Improved fermentation process for producing the Gram-positive antibiotic A47934 which comprises cultivating a new strain of Streptomyces toyocaensis, NRRL 18112, and a biologically purified culture of this microorganism are provided. |
| 4713331 |
Microbial production of A41030 antibiotics |
December 15, 1987 |
| Antibiotic A41030, a complex of 7 individual factors, is produced by submerged, aerobic fermentation of new Streptomyces virginiae NRRL 12525, and Streptomyces virginiae NRRL 15156. The antibiotic factors are separated and possess antibacterial activity against Staphylococcus and Str |
| 4663282 |
Glycopeptide antibiotic CUC/CSV and process for its production |
May 5, 1987 |
| New glycopeptide antibiotic CUC/CSV which has the formula: ##STR1## wherein R is L-ristosaminyl;R.sub.1 is the disaccharide mannosyl-glucosyl; andR.sub.2 and R.sub.3 are mannosyl, and its salts, particularly the pharmaceutically acceptable salts, are useful new antibiotics are active |
| 4604239 |
Antibiotics |
August 5, 1986 |
| Antibiotic A41030, a complex of 7 individual factors, is produced by submerged, aerobic fermentation of new Streptomyces virginiae NRRL 12525, and Streptomyces virginiae NRRL 15156. The antibiotic factors are separated and possess antibacterial activity against Staphylococcus and Str |
| 4563442 |
Glycopeptide bioconversion products |
January 7, 1986 |
| New glycopeptide antibiotics of the formula: ##STR1## wherein W is the remaining portion of a glycopeptide antibiotic selected from actaplanin factors B.sub.1, B.sub.2, B.sub.3, C.sub.1, C.sub.2, C.sub.3, D.sub.1, D.sub.2, E.sub.1, G, K, L, M, N, O and actaplanin .psi.aglycone, a |
| 4559323 |
A41030 Antibiotics |
December 17, 1985 |
| Antibiotic A41030, a complex of 7 individual factors, is produced by submerged, aerobic fermentation of new Streptomyces virginiae NRRL 12525, and Streptomyces virginiae NRRL 15156. The antibiotic factors are separated and possess antibacterial activity against Staphylococcus and Str |
| 4548924 |
Antibiotics M43B and M43C, pharmaceutical composition and method of use |
October 22, 1985 |
| Antibiotics M43B and M43C, new glycopeptide antibiotics of the vancomycin class, are produced by Nocardia orientalis NRRL 2452. M43B and M43C have antibacterial activity. |
| 4537777 |
A52688 Antibiotics and process for their production |
August 27, 1985 |
| New A52688 factors A, C, D, E, F, G, H, J and K which have the common general formula: ##STR1## are antibacterial and antineoplastic agents. Methods of preparing the antibiotics by culturing a strain of Mycoleptodiscus terrestris are provided. |
| 4537770 |
A41030 antibiotics |
August 27, 1985 |
| Antibiotic A41030, a complex of 7 individual factors, is produced by submerged, aerobic fermentation of new Streptomyces virginiae NRRL 12525, and Streptomyces virginiae NRRL 15156. The antiobiotic factors are separated and possess antibacterial activity against Staphylococcus and St |
| 4537715 |
Glycopeptide antibiotic CUC/CSV and process for its production |
August 27, 1985 |
| New glycopeptide antibiotic CUC/CSV which has the formula: ##STR1## wherein R is L-ristosaminyl;R.sub.1 is the disaccharide mannosyl-glucosyl; andR.sub.2 and R.sub.3 are mannosyl, and its salts, particularly the pharmaceutically acceptable salts, are useful new antibiotics are active |
| 4492650 |
A54556 Antibiotics and process for production thereof |
January 8, 1985 |
| Antibiotic A54556, a complex of 8 individual factors, produced by submerged, aerobic fermentation of new Streptomyces hawaiiensis NRRL 15010. The complex and the individual, separated factors are active against Staphylococcus and Streptococcus which are penicillin resistant. |
| 4431809 |
Antibiotic A-33853 derivatives |
February 14, 1984 |
| Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic and the diacetyl and triacetyl derivatives thereof disclosed herein have shown antibacterial activity against Staphylococcus and Streptococcus species which are penicill |
| 4400510 |
A-32256 Phenazine antibiotic |
August 23, 1983 |
| Antibiotic A-32256 which is produced by submerged, aerobic fermentation of a Streptomyces sp. NRRL 12067. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus and various anaerobic species. In addition, the antibiotic has shown antitrichomonas activity |
| 4329472 |
Antibiotic A-33853 and the tetraacetyl derivative thereof |
May 11, 1982 |
| Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus species which are penicillin resistant. In addition, the antibiotic has shown antirival and |
| 4316959 |
Process for production of antibiotic from streptomyces |
February 23, 1982 |
| Antibiotic A-32256 which is produced by submerged, aerobic fermentation of a Streptomyces sp. NRRL 12067. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus and various anaerobic species. In addition, the antibiotic has shown antitrichomonas activity |
| 4293649 |
Process for production of antibiotic A-33853 |
October 6, 1981 |
| Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus species which are penicillin resistant. In addition, the antibiotic has shown antiviral and |
| 4247542 |
A-40104 Antibiotics and process for production thereof |
January 27, 1981 |
| A-40104 antibiotic complex, comprising active factors A, B, C, and D, produced by submerged aerobic fermentation of Clitopilus pseudo-pinsitus. Individual factors A, B, and C have been isolated. A-40104 factor C is the known antibiotic pleuromutilin. A-40104 factors A and B are novel |
| 4131547 |
Refillable column for chromatography at elevated pressure |
December 26, 1978 |
| A refillable column for chromatography at elevated pressure is described comprised of a cylinder connected on both ends to a coupling having internal threads and an annular shoulder at the internal terminus of the threads. A plug having external threads is disposed in said coupling and |
| 4129721 |
A-40104 antibiotics and process for production thereof |
December 12, 1978 |
| A-40104 antibiotic complex, comprising active factors A, B, C, and D, produced by submerged aerobic fermentation of Clitopilus pseudo-pinsitus. Individual factors, A, B, and C have been isolated. A-40104 factor C is the known antibiotic pleuromutilin. A-40104 factors A and B are novel |
| 4122168 |
Antibiotic A-35512 and process for production thereof |
October 24, 1978 |
| Antibiotic A-35512 complex, comprising microbiologically active, related factors A, B, C, E and H, is produced by submerged aerobic fermentation of Streptomyces candidus NRRL 8156. The individual A-35512 factors are separated and isolated by chromatography. The A-35512 antibiotics are |
| 4083964 |
Antibiotic A-35512 for increasing feed utilization efficiency in an animal |
April 11, 1978 |
| Antibiotic A-35512 complex, comprising microbiologically active, related factors A, B, C, E and H, is produced by submerged aerobic fermentation of Streptomyces candidus NRRL 8156. The individual A-35512 factors are separated and isolated by chromatography. The A-35512 antibiotics are |
| 4024246 |
Antibiotic A-22082 and process for production thereof |
May 17, 1977 |
| Antibiotic A-22082 is produced by submerged aerobic fermentation of Aspergillus nidulans NRRL 8112. Antibiotic A-22082 is an antifungal agent. |
| 4024245 |
Antibiotic A-30912 and process for production thereof |
May 17, 1977 |
| Antibiotic A-30912 complex, comprising microbiologically active, structurally related factors A, B, C, D, E, F and G, is produced by submerged aerobic fermentation of Aspergillus rugulosus NRRL 8113. The A-30912 factors A, B, C, D, E, F, and G are separated from the A-30912 complex b |
| 3954972 |
Antibiotic A-26771 factor |
May 4, 1976 |
| Antibiotic mixture A-26771, comprising microbiologically active factors A, B and C, produced by fermentation of Penicillium turbatum Westling NRRL 5630, and isolation and separation of the individual factors thereof by extraction, chromatography and crystallization. The A-26771 mixture a |
| 3932219 |
Antibiotic A-26771 factors and process for production thereof |
January 13, 1976 |
| Antibiotic mixture A-26771, comprising microbiologically active factors A, B and C, produced by fermentation of Penicillium turbatum Westling NRRL 5630, and isolation and separation of the individual factors thereof by extraction, chromatography and crystallization. The A-26771 mixture a |
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