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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Merrill; Edward W.
Address:
Belmont, MA
No. of patents:
21
Patents:












Patent Number Title Of Patent Date Issued
8563623 Radiation melt treated ultra high molecular weight polyethylene prosthetic devices October 22, 2013
A medical prosthesis for use within the body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radicals, is described. Preferred prostheses exhibit reduced production of particles from the prosthesis during wear of the
8263676 Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices September 11, 2012
A medical prosthesis for use within the body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radicals, is described. Preferred prostheses exhibit reduced production of particles from the prosthesis during wear of the
8066512 Method for occlusal position measurement and recording November 29, 2011
The occlusal position of a patient is measured by means of light transmission through a layer of a polysiloxane which is not cross-linked. This material forms an exceptionally accurate impression of a patient's bite essentially instantaneously and enables subsequent recording and ana
7858671 Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices December 28, 2010
A medical prosthesis for use within the body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radicals, is described. Preferred prostheses exhibit reduced production of particles from the prosthesis during wear of the
7008634 Cell growth substrates with tethered cell growth effector molecules March 7, 2006
Described are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a solid substrate. The compositions
6786933 Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices September 7, 2004
A medical prosthesis for use within a body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radial. Preferred prosthesis exhibits reduced production of particles from the prosthesis during wear of the prosthesis, and ar
6641617 Radiation and melt treated ultra high molecular weight polyethylene prosthetic device and method November 4, 2003
A medical prosthesis for use within the body which is formed of radiation treated ultra high molecular weight polyethylene having substantially no detectable free radicals, is described. Preferred prostheses exhibit reduced production of particles from the prosthesis during wear of the
6616982 Poly(ethylene oxide) coated surfaces September 9, 2003
Methods are provided for the fabrication of hydrophilic coatings on hydrophobic surfaces. In one embodiment, a polyethylene oxide (PEO) coating is fabricated on the surface of a polymeric material by contacting the surface with a methacrylic acid or acrylic acid monomer. The monomer
6509098 Poly(ethylene oxide) coated surfaces January 21, 2003
Methods are provided for the fabrication of hydrophilic coatings on hydrophobic surfaces. In one embodiment, a polyethylene oxide (PEO) coating is fabricated on the surface of a polymeric material by contacting the surface with a methacrylic acid or acrylic acid monomer. The monomer
6464926 Process of making ultra high molecular weight polyethylene prosthetic devices October 15, 2002
The present invention relates to a medical prosthesis for use within the body, which is formed of ultra high molecular weight polyethylene having a polymeric structure with less than about 50% crystallinity, less than about 290 .ANG. lamellar thickness and less than about 940 MPa tensile
6045818 Cell growth substrates with tethered cell growth effector molecules April 4, 2000
Disclosed are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a solid substrate. The compositions
5906828 Cell growth substrates with tethered cell growth effector molecules May 25, 1999
Disclosed are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a solid substrate. The compositions
5879400 Melt-irradiated ultra high molecular weight polyethylene prosthetic devices March 9, 1999
A medical prosthesis for use within the body which is formed of ultra high molecular weight polyethylene which has a polymeric structure with less than about 50% crystallinity, less than about 290 .ANG. lamellar thickness and less than about 940 MPa tensile elastic modulus, so as to redu
5836313 Methods for making composite hydrogels for corneal prostheses November 17, 1998
Methods for forming implantable composite keratoprostheses are provided. The methods provide keratoprostheses designed to provide a suitable substrate for corneal epithelial cell growth while maintaining the desirable characteristics of hydrogels, i.e., clarity, flexibility and the a
5830986 Methods for the synthesis of functionalizable poly(ethylene oxide) star macromolecules November 3, 1998
Methods are provided for the synthesis of poly(ethylene oxide) ("PEO") star macromolecules including functionalizable groups. In one embodiment, a core molecule including a plurality of dendritic branches or having a comb structure, and including a plurality of accessible reactive groups
5459258 Polysaccharide based biodegradable thermoplastic materials October 17, 1995
A thermoplastic biodegradable material is prepared from a continuous hydrophobic polysaccharide phase and a discontinuous phase of dispersed unmodified polysaccharide or bicontinuous phases of both. The material is easily processed into a wide variety of articles of manufacture that have
5275838 Immobilized polyethylene oxide star molecules for bioapplications January 4, 1994
A method for immobilizing polyethylene oxide (PEO) star molecules in the form of hydrogel layers and a product thereof are disclosed. The PEO star molecules are biocompatible and demonstrate non-thrombogenic properties. As such, the PEO star molecule layers have numerous biomedical a
5171264 Immobilized polyethylene oxide star molecules for bioapplications December 15, 1992
This invention pertains to a method for immobilizing polyethylene oxide (PEO) star molecules in the form of hydrogels. the PEO star molecules are biocompatible and demonstrate non-thrombogenic properties. As such, the PEO star molecules have numerous uses for biomedical applications. The
4910015 Surface-active polysiloxanes and drug releasing materials thereof March 20, 1990
A crosslinked polymer network comprising the reaction product of a polyethylene oxide and a polyglycidoxypropylsiloxane is described. These materials form hydrogel networks having very high partition coefficients for selected pharmaceuticals and are suitable for controlled drug release
4906465 Antithrombogenic devices containing polysiloxanes March 6, 1990
A crosslinked polymer network comprising the reaction product of a polyethylene oxide and a polyglycidoxypropylsiloxane is described. These materials demonstrate low in vivo platelet retention as well as a low thrombogenicity. As such, they can provide antithrombogenic properties to
4884577 Process and apparatus for measuring blood viscosity directly and rapidly December 5, 1989
Apparatus for rapidly measuring blood viscosity including a hollow column of narrow bore in fluid communication with a chamber containing a porous bed and means for measuring blood flow rate within the column. The specific permeability of the bed and the pressure gradient are selected so










 
 
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