| Patent Number |
Title Of Patent |
Date Issued |
| 7618448 |
Polymeric, degradable drug-eluting stents and coatings |
November 17, 2009 |
| Absorbable stents and absorbable stent coatings have been developed with improved properties. These devices preferably comprise biocompatible copolymers or homopolymers of 4-hydroxybutyrate, and optionally poly-L-lactic acid and other absorbable polymers and additives. Compositions o |
| 7553923 |
Medical devices and applications of polyhydroxyalkanoate polymers |
June 30, 2009 |
| Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws |
| 7268205 |
Medical devices and applications of polyhydroxyalkanoate polymers |
September 11, 2007 |
| Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws |
| 7244442 |
Method for making devices using polyhydroxyalkanoate having pyrogen removed |
July 17, 2007 |
| Polyhydroxyalkanoates (PHAs) from which pyrogen has been removed are provided for use in numerous biomedical applications. PHAs which have been chemically modified to enhance physical and/or chemical properties, for targeting or to modify biodegradability or clearance by the reticulo |
| 7229804 |
Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids |
June 12, 2007 |
| The gene encoding a 4-hydroxybutyryl-CoA transferase has been isolated from bacteria and integrated into the genome of bacteria also expressing a polyhydroxyalkanoate synthase, to yield an improved production process for 4HB-containing polyhydroxyalkanoates using transgenic organisms, |
| 7179883 |
Medical devices and applications of polyhydroxyalkanoate polymers |
February 20, 2007 |
| Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws |
| 7081357 |
Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids |
July 25, 2006 |
| The gene encoding a 4-hydroxybutyryl-CoA transferase has been isolated from bacteria and integrated into the genome of bacteria also expressing a polyhydroxyalkanoate synthase, to yield an improved production process for 4HB-containing polyhydroxyalkanoates using transgenic organisms, |
| 7025980 |
Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation |
April 11, 2006 |
| Polyhydroxyalkanoate materials are provided which are suitable for repair of soft tissue, augmentation, and as viscosupplements in animals, particularly humans. The materials comprise liquid polyhydroxyalkanoate polymer compositions or polyhydroxyalkanoate microdispersions. Devices a |
| 6878758 |
Polyhydroxyalkanoate compositions having controlled degradation rates |
April 12, 2005 |
| Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or inc |
| 6867248 |
Polyhydroxyalkanoate compositions having controlled degradation rates |
March 15, 2005 |
| Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or inc |
| 6867247 |
Medical devices and applications of polyhydroxyalkanoate polymers |
March 15, 2005 |
| Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws |
| 6838493 |
Medical devices and applications of polyhydroxyalkanoate polymers |
January 4, 2005 |
| Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws |
| 6828357 |
Polyhydroxyalkanoate compositions having controlled degradation rates |
December 7, 2004 |
| Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or inc |
| 6709848 |
Methods for isolating polyhydroxyalkanoates from plants |
March 23, 2004 |
| Methods are provided for separating polyhydroxyalkanoates ("PHAs") from plants, such as transgenic oil crop plants. The methods advantageously permit both the oil and the PHAs to be recovered from the plant biomass. To isolate the PHAs, in one embodiment, a biomass derived from an oil cr |
| 6689589 |
Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids |
February 10, 2004 |
| The gene encoding a 4-hydroxybutyryl-Co A transferase has been isolated from bacteria and integrated into the genome of bacteria also expressing a polyhydroxyalkanoate synthase, to yield an improved production process for 4HB-containing polyhydroxyalkanoates using transgenic organisms, i |
| 6623749 |
Medical device containing polyhydroxyalkanoate treated with oxidizing agent to remove endotoxin |
September 23, 2003 |
| Polyhydroxyalkanoate (PHA) that contains a pyrogen such as an endotoxin due to a process of producing the PHA is treated to remove the pyrogen by a process that does not affect the inherent chemical and physical properties of the PHA to obtain a biocompatible PHA. PHA produced by ferment |
| 6623730 |
Therapeutic uses of polymers and oligomers comprising gamma-hydroxybutyrate |
September 23, 2003 |
| Oligomers and polymer compositions are provided which comprise GHB and produce GHB after administration in vivo. Devices for the storage and delivery of these polymers and oligomers are also provided. These oligomers and polymer compositions are useful in a variety of applications. T |
| 6610764 |
Polyhydroxyalkanoate compositions having controlled degradation rates |
August 26, 2003 |
| Biocompatible polyhydroxyalkanoate compositions with controlled degradation rates have been developed. In one embodiment, the polyhydroxyalkanoates contain additives to alter the degradation rates. In another embodiment, the polyhydroxyalkanoates are formed of mixtures of monomers or inc |
| 6585994 |
Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation |
July 1, 2003 |
| Polyhydroxyalkanoate materials are provided which are suitable for repair of soft tissue, augmentation, and as viscosupplements in animals, particularly humans. The materials comprise liquid polyhydroxyalkanoate polymer compositions or polyhydroxyalkanoate microdispersions. Devices a |
| 6555123 |
Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation |
April 29, 2003 |
| Polyhydroxyalkanoate materials are provided which are suitable for repair of soft tissue, augmentation, and as viscosupplements in animals, particularly humans. The materials comprise liquid polyhydroxyalkanoate polymer compositions or polyhydroxyalkanoate microdispersions. Devices a |
| 6548569 |
Medical devices and applications of polyhydroxyalkanoate polymers |
April 15, 2003 |
| Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws |
| 6380244 |
Nutritional and therapeutic uses of 3-hydroxyalkanoate oligomers |
April 30, 2002 |
| Nutritional or therapeutic compositions are provided for increasing ketone body levels in the blood of mammals by providing a source of ketone bodies in the form of linear or cyclic oligomers and/or derivatives of 3-hydroxyacids. The 3-hydroxyacid can be in the form of a linear oligomer |
| 6316262 |
Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids |
November 13, 2001 |
| The gene encoding a 4-hydroxybutyryl-Co A transferase has been isolated from bacteria and integrated into the genome of bacteria also expressing a polyhydroxyalkanoate synthase, to yield an improved production process for 4HB-containing polyhydroxyalkanoates using transgenic organisms, i |
| 6245537 |
Removing endotoxin with an oxdizing agent from polyhydroxyalkanoates produced by fermentation |
June 12, 2001 |
| Polyhydroxyalkanoate (PHA) that contains a pyrogen such as endotoxin due to a process of producing the PHA is treated to remove the pyrogen by a process that does not affect the inherent chemical and physical properties of the PHA to obtain a biocompatible PHA. PHA produced by fermentati |
| 6083729 |
Methods for isolating polyhydroxyalkanoates from plants |
July 4, 2000 |
| Methods are provided for separating polyhydroxyalkanoates ("PHAs") from plants, such as transgenic oil crop plants. The methods advantageously permit both the oil and the PHAs to be recovered from the plant biomass. To isolate the PHAs, in one embodiment, a biomass derived from an oil cr |
