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Marliere; Philippe
Etiolles, FR
No. of patents:

Patent Number Title Of Patent Date Issued
7960103 Method for obtaining new life forms June 14, 2011
The present invention relates to a method for generating a novel form of life comprising the steps consisting of: a) irreversible alteration of the genome of a microbial clone; b) cultivation of a vast population of microbial cells originating from the altered clone obtained in step a)
7736899 Cells and method for producing proteins comprising an unconventional amino acid June 15, 2010
The present invention relates to a method for providing bacterial or yeast cells with the capacity to produce a protein, the amino acid sequence of which comprises at least one unconventional amino acid. The method involves (a) introducing at least one missense mutation in a target codon
7524646 Method for diversifying the chemical composition of proteins produced in vivo by genetically dis April 28, 2009
The present invention is directed to a method to diversify the chemical composition of proteins produced in vivo comprising the step of disabling, particularly by mutagenesis, the editing function of one of its aminoacyl tRNA synthetases. The present invention is also directed to nuc
7425530 Stereoselective preparation of cyclic L-amino acids September 16, 2008
The invention concerns a method for producing a cyclic L-amino acid of formula (I), characterised in that it consists in reacting a L-diamino acid of formula (II) or an enantiomeric mixture comprising such a L-diamino acid and a corresponding D-diamino acid in variable proportions, i
7381555 Lactobacillus N-deoxyribosyl transferases, corresponding nucleotide sequences and their uses June 3, 2008
The invention concerns novel polypeptides and their fragments, isolated from Lactobacillus, having at least a N-deoxyribosyl transferase activity, the polynucleotides encoding said polypeptides, cloning and/or expression vectors including said polynucleotides, cells transformed by sa
7319148 Combinatorial production of nucleotide and nucleoside (XiTP) analogues January 15, 2008
The invention concerns novel nucleotide analogues comprising a reactive hydrazide function used as initial synthons for preparing compounds (formula I) capable of inducing mutations or capable of inhibiting a DNA polymerase or a kinase. The invention also concerns nucleic acids compr
7229797 Enzymatic synthesis of deoxyribonucleosides June 12, 2007
The present invention relates to a method for the in vitro enzymatic synthesis of deoxyribonucleosides and enzymes suitable for this method.
6686194 Method and device for selecting accelerated proliferation of living cells in suspension February 3, 2004
The present invention relates to a method and a device for selecting accelerated proliferation of living cells in suspension. The culture apparatus (2) of the present invention enables cells to proliferate in suspension over unlimited periods of time. Natural selection results in the

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