| Patent Number |
Title Of Patent |
Date Issued |
| RE38723 |
Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells |
April 12, 2005 |
| The subject invention provides substrates useful for analyzing the metabolic activity in cells by improving the retention of a detectable reporter molecule only in intact cells where a particular enzyme is present. In particular, improved retention results from a two part process inv |
| 6291203 |
Cyanine dyes that stain cells and mitochondria |
September 18, 2001 |
| The present invention relates to the use of positively-charged unsymmetrical cyanine dyes, including novel unsymmetrical cyanine dyes, to stain cells and selectively stain intracellular organelles, with particular advantages in staining mitochondria. The dyes are generally weakly flu |
| 6162931 |
Fluorinated xanthene derivatives |
December 19, 2000 |
| The family of dyes of the invention are fluoresceins and rhodols that are directly substituted on one or more aromatic carbons by fluorine. These fluorine-substituted fluorescent dyes possess greater photostability and have lower sensitivity to pH changes in the physiological range of 6- |
| 6130101 |
Sulfonated xanthene derivatives |
October 10, 2000 |
| The present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulfonic acid. The dyes of the invention, including chemically reactive dyes and dye-conjugates are useful as fluores |
| 6004536 |
Lipophilic cyanine dyes with enchanced aqueous solubilty |
December 21, 1999 |
| The present invention relates to a family of cyanine dyes possessing lipophilic alkyl chains and either one or more reactive functional groups, bromo or chloro, or phenyl, sulfophenyl or polysulfophenyl substituents or combinations thereof. The dyes of the invention are useful for staini |
| 5696157 |
Sulfonated derivatives of 7-aminocoumarin |
December 9, 1997 |
| The present invention describes 7-aminocoumarin dyes that are substituted one or more times at the 3-, 6- and/or 8-positions by a sulfonic acid or a salt of a sulfonic acid, said dyes being useful as fluorescent probes or in the preparation of enzyme substrates, caged probes, or adducts |
| 5576424 |
Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells |
November 19, 1996 |
| The subject invention provides substrates useful for analyzing the metabolic activity in cells by improving the retention of a detectable reporter molecule only in intact cells where a particular enzyme is present. In particular, improved retention results from a two part process inv |
