| Patent Number |
Title Of Patent |
Date Issued |
| 8063185 |
Refolded recombinant .beta.-secretase crystals and methods for preparing and using the same |
November 22, 2011 |
| The present application relates to methods for growing crystals of both the uncomplexed and complexed forms of .beta.-secretase (BACE) polypeptide. The present application also relates to crystalline forms of uncomplexed BACE and the three-dimensional structure of BACE, as determined |
| 7816339 |
Treatments for Flaviviridae virus infection |
October 19, 2010 |
| The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host. |
| 7772178 |
Pharmaceutical formulations and methods of treatment using the same |
August 10, 2010 |
| Pharmaceutical formulations containing at least one compound of Formulae I-XXVI herein and at least one surfactant. Pharmaceutically acceptable carriers and excipients may also be included in the formulations. The formulations of the present invention are suited for use in single unit |
| 7569391 |
Method for making .beta.-secretase co-crystals complexed with a ligand |
August 4, 2009 |
| The present application relates to methods for growing crystals of both the uncomplexed and complexed forms of .beta.-secretase (BACE) polypeptide. The present application also relates to crystalline forms of uncomplexed BACE and the three-dimensional structure of BACE, as determined |