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Inventor:
Malcolm; Bruce A.
Address:
Paoli, PA
No. of patents:
4
Patents:












Patent Number Title Of Patent Date Issued
8063185 Refolded recombinant .beta.-secretase crystals and methods for preparing and using the same November 22, 2011
The present application relates to methods for growing crystals of both the uncomplexed and complexed forms of .beta.-secretase (BACE) polypeptide. The present application also relates to crystalline forms of uncomplexed BACE and the three-dimensional structure of BACE, as determined
7816339 Treatments for Flaviviridae virus infection October 19, 2010
The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
7772178 Pharmaceutical formulations and methods of treatment using the same August 10, 2010
Pharmaceutical formulations containing at least one compound of Formulae I-XXVI herein and at least one surfactant. Pharmaceutically acceptable carriers and excipients may also be included in the formulations. The formulations of the present invention are suited for use in single unit
7569391 Method for making .beta.-secretase co-crystals complexed with a ligand August 4, 2009
The present application relates to methods for growing crystals of both the uncomplexed and complexed forms of .beta.-secretase (BACE) polypeptide. The present application also relates to crystalline forms of uncomplexed BACE and the three-dimensional structure of BACE, as determined










 
 
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