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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
MacKenzie; Alexander E.
Address:
Ottawa, CA
No. of patents:
15
Patents:












Patent Number Title Of Patent Date Issued
7776552 Mammalian IAP gene family, primers, probes and detection methods August 17, 2010
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primer and probes for the identi
7235372 Use of neuronal apoptosis inhibitor protein (NAIP) June 26, 2007
The invention provides a novel NAIP nucleic and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
7067281 Mammalian IAP gene family, primers, probes and detection methods June 27, 2006
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and
6994957 Use of neuronal apoptosis inhibitor protein (NAIP) February 7, 2006
The invention provides NAIP nucleic acid and sequences. Also provided are anti-NAIP antibodies and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
6977158 Mammalian IAP gene family, primers, probes, and detection methods December 20, 2005
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and
6946544 XAF genes and polypeptides: methods and reagents for modulating apoptosis September 20, 2005
The invention provides novel XAF nucleic acid sequences. Also provided are XAF polypeptides, anti-XAF antibodies, and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
6709866 Methods for enhancing survival of a neuron March 23, 2004
NAIP and IAP polypeptides prevent neuronal cell death caused by ischemia, neurodegenerative conditions, and axotomy. The invention provides methods for neuroprotection by the prevention of cell death and kits and methods for the identification of neuroprotective therapeutic compounds.
6689562 Mammalian IAP gene family, primers, probes and detection methods February 10, 2004
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and
6656704 Mammalian apoptosis inhibitor protein gene family, primers, probes and detection methods December 2, 2003
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and
6541457 Mammalian IAP gene family, primers, probes and detection methods April 1, 2003
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP-family and
6495339 Method of identifying a compound that modulates XAF-mediated apoptosis December 17, 2002
The invention provides novel XAF nucleic acid sequences. Also provided are XAF polypeptides, anti-XAF antibodies, and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
6159948 Therapeutic and drug screening methods for the treatment and prevention of neuronal disease December 12, 2000
NAIP and IAP polypeptides prevent neuronal cell death caused by ischemia, neurodegenerative conditions, and axotomy. The invention provides methods for neuroprotection by the prevention of cell death and kits and methods for the identification of neuroprotective therapeutic compounds.
6156535 Mammalian IAP gene family, primers, probes, and detection methods December 5, 2000
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and
6107088 XAF genes and polypeptides: methods and reagents for modulating apoptosis August 22, 2000
The invention provides novel XAF nucleic acid sequences. Also provided are XAF polypeptides, anti-XAF antibodies, and methods for modulating apoptosis and detecting compounds which modulate apoptosis.
5919912 Mammalian IAP antibodies and diagnostic kits July 6, 1999
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and










 
 
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