Resources Contact Us Home
Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Luly; Jay R.
Address:
Libertyville, IL
No. of patents:
38
Patents:












Patent Number Title Of Patent Date Issued
5731320 Macrocyclic amide and urea immunomodulators March 24, 1998
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antii
5708002 Macrocyclic immunomodulators January 13, 1998
Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same.
5672605 Macrolide immunomodulators September 30, 1997
Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, processes for the preparation of the compounds of the invention, intermediates useful in these processes, a pharmaceutical composition, and a method of tr
5663148 Anaphylatoxin receptor ligands containing lipophilic residues September 2, 1997
Oligopeptide compounds or oligopeptide analague compounds of the formula, A-B-D-E-G-J-L-M-N(R.sup.4)Arg-OH, which are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states, as well as anaphylatoxin receptor ligand compositions and a method
5643918 Marcrocyclic amide and urea immunomodulators July 1, 1997
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antii
5612350 Macrocyclic immunomodulators with novel cyclohexyl ring replacements March 18, 1997
Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is a substituent selected from among radicals having the subformulae ##STR2## and other heterocyclic radicals, as well as pharmaceutical com
5604294 Macrocyclic immunomodulators February 18, 1997
Immunomodulatory macrocyclic compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein Y is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same and methods of
5604234 Substituted thiol macrolactam immunomodulators February 18, 1997
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing such compounds and therapeutic methods of their use.
5599927 Macrocyclic immunomodulators with novel cyclohexyl ring replacements February 4, 1997
Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is a substituent selected from among radicals having the subformulae ##STR2## and other heterocyclic radicals, as well as pharmaceutical com
5583139 Marcolide immunomodulators December 10, 1996
Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, processes for the preparation of the compounds of the invention, intermediates useful in these processes, a pharmaceutical composition, and a method of tr
5563172 Macrocyclic amide and urea immunomodulators October 8, 1996
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antii
5561228 Macrocyclic immunomodulators October 1, 1996
Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is a group having the formula ##STR2## as well as pharmaceutical compositions containing the same.
5561140 Substituted alicyclic amine-containing macrocyclic immunomodulators October 1, 1996
Compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a group having the formula ##STR2## as well as pharmaceutically co
5561139 Substituted alicyclic-aliphatic amine-containing macrocyclic immunomodulators October 1, 1996
Compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a radical having the formula ##STR2## as well as pharmaceutica
5561137 Thio-heterocyclic macrolactam immunomodulators October 1, 1996
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof,where R.sup.8 and R.sup.9 are selected such that one of R.sup.8 and R.sup.9 is hydrogen and the other is --S(O).sub.s --heterocyclic,as well
5541193 Heterocycle-containing macrocyclic immunomodulators July 30, 1996
Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.107, R.sup.108, R.sup.109 and R.sup.110 is a radical having the formula ##STR2## as well as pharmaceutically com
5541189 Substituted aliphatic amine-containing macrocyclic immunomodulators July 30, 1996
Compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a radical having the formula ##STR2## as well as pharmaceutica
5534632 Macrocyclic carbamate immunomodulators July 9, 1996
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein R.sup.8 and R.sup.9 are selected such that one of R.sup.8 and R.sup.9 is hydrogen, and the other is chosen from the group consis
5530120 Substituted alicyclic aliphatic-amine containing macrocyclic immunomodulators June 25, 1996
Compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a radical having the formula ##STR2## as well as pharmaceutica
5530119 Substituted alicyclic amine-containing macrocyclic immunomodulators June 25, 1996
Compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein one of R.sup.104 and R.sup.105 is hydrogen, and the other of R.sup.104 and R.sup.105 is a group having the formula ##STR2## as well as pharmaceutically co
5527907 Macrolide immunomodulators June 18, 1996
Novel macrolide compounds of the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, processes for the preparation of the compounds of the invention, intermediates useful in these processes, a pharmaceutical composition, and a method of tr
5508397 Activated macrolactams April 16, 1996
Activated macrolactam compounds having the formula ##STR1## wherein n is zero or one, R.sup.101 is selected from the group consisting of methyl, ethyl, allyl, propyl and cyclopropylmethyl;R.sup.102 is hydrogen, and R.sup.103 is selected from the group consisting of hydrogen, hydroxy
5457111 Macrocyclic immunomodulators October 10, 1995
Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same.
5387671 Hexa- and heptapeptide anaphylatoxin-receptor ligands February 7, 1995
Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L-M-Q are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states.Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating a
5386011 Hexapeptide anaphylatoxin-receptor ligands January 31, 1995
Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L-M-Q are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states.Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating a
5223485 Anaphylatoxin-receptor ligands June 29, 1993
Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L-M-Q-T are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states. Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulatin
5214129 Peptidylaminodiols May 25, 1993
A renin inhibiting compound of the formula: ##STR1## wherein A is a substituent; W is C.dbd.O or CHOH; U is CH.sub.2 or NR.sub.2, provided that when W is CHOH then U is CH.sub.2 ; R.sub.1 is loweralkyl, cycloalkylmethyl, benzyl, 4-methoxybenzyl, halobenzyl, (1-naphthyl)methyl, (2
5190922 Terminally modified tri-, tetra- and pentapeptide anaphylatoxin receptor ligands March 2, 1993
Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states. Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating
5091575 Peptidylaminodiols February 25, 1992
A renin inhibiting compound of the formula: ##STR1## wherein A is a substituent; W is C.dbd.O or CHOH; U is CH.sub.2 or NR.sup.2, provided that when W is CHOH then U is CH.sub.2 ; R.sub.1 is loweralkyl, cycloalkylmethyl, benzyl, 4-methoxybenzyl, halobenzyl, (1-naphthyl)methyl, (2
5032577 Peptidylaminodiols July 16, 1991
A renin inhibiting compound of the formula: ##STR1## wherein A is a substituent; W is C.dbd.O or CHOH; U is CH.sub.2 or NR.sub.2, provided that when W is CHOH then U is CH.sub.2 ; R.sub.1 is loweralkyl, cycloalkylmethyl, benzyl, 4-methoxybenzyl, halobenzyl, (1-naphthyl)methyl, (2
4977277 Functionalized peptidyl aminodiols and -triols 4-amino-5-cyclohexyl-3-hydroxy-1,2-oxopentane and December 11, 1990
The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is hydrogen; loweralkyl; arylalkyl; OR.sub.8 or SR.sub.8 wherein R.sub.8 is hydrogen, loweralkyl or aminoalkyl; NR.sub.9 R.sub.10 wherein R.sub.9 and R.sub.10 are independently selected from hydroge
4857507 Angiotensinogen analogs August 15, 1989
The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is hydrogen; loweralkyl; arylalkyl; OR.sub.10 or SR.sub.10 wherein R.sub.10 is hydrogen, loweralkyl or aminoalkyl; NR.sub.11 R.sub.12 wherein R.sub.11 and R.sub.12 are independently selected from hy
4845079 Peptidylaminodiols July 4, 1989
A renin inhibiting compound of the formula: ##STR1## wherein A is a substituent; W is C.dbd.O or CHOH; U is CH.sub.2 or NR.sub.2, provided that when W is CHOH then U is CH.sub.2 ; R.sub.1 is loweralkyl, cycloalkylmethyl, benzyl, 4-methoxybenzyl, halobenzyl, (1-naphthyl)methyl, (2
4837204 Functionalized peptidyl aminodiols and -triols June 6, 1989
The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is hydrogen; loweralkyl; aryalkyl; OR.sub.8 or SR.sub.8 wherein R.sub.8 is hydrogen, loweralkyl or aminoalkyl; NR.sub.9 R.sub.10 wherein R.sub.9 and R.sub.10 are independently selected from hydrogen
4826815 Renin inhibiting compounds May 2, 1989
The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is hydrogen; loweralkyl; arylalkyl; Or.sub.10 wherein R.sub.10 is hydrogen or loweralkyl; NR.sub.11 R.sub.12 wherein R.sub.11 and R.sub.12 are independently selected from hydrogen and loweralkyl; or
4725584 Peptidyl-1-amino-2,4-diols February 16, 1988
The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is an N-protecting group; R.sub.1, R.sub.2, R.sub.3 and R.sub.5 are independently selected from loweralkyl or lipophilic or aromatic amino acid side chains; and R.sub.4 is hydrogen, loweralkyl, lowe
4725583 Functionalized peptidylaminoalcohols February 16, 1988
The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is an N-protecting group; R.sub.1, R.sub.2 and R.sub.3 are independently selected from loweralkyl or lipophilic or aromatic amino acid side chains; and R.sub.4 is --CHO, --CO.sub.2 H, halomethyl or
4680284 Modified phenylalanine peptidylaminodiols July 14, 1987
The invention relates to renin inhibiting compounds of the formula: ##STR1## wherein R.sub.2 is loweralkyl or arylalkyl; R.sub.3 is loweralkyl; X is ##STR2## wherein A is hydrogen or an N-protecting group, R.sub.1 is loweralkyl or arylalkyl, m is 1-3, n is 1-3, p is 1-3, q is 1-3










 
 
  Recently Added Patents
Systems and methods for providing television signals using a network interface device
Program recording medium, image processing apparatus, imaging apparatus, and image processing method
Dimmer system and damper circuit thereof
(Meth)acrylic resin composition, imidized (meth)acrylic resin composition, and film obtained by molding them
Method for programming non-volatile memory device and apparatuses performing the method
Graphical user interfaces and occlusion prevention for fisheye lenses with line segment foci
Methods and systems for use in tracking targets for direction finding systems
  Randomly Featured Patents
Method for installing an auxiliary unit on a computer
Percussion mallet
Precipitation of multivalent antiligands with affinity surfactants
Display screen with graphical user interface
Extruded snack resembling corn on the cob
Film advance and metering mechanism for cameras
Composite spring-lock coupling
Method of fabricating a semiconductor device
Microstrip for wireless communication and method for designing the same
Indole derivatives