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Inventor: Lou; Yan
Address: San Jose, CA
No. of patents: 10
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| 8119636 |
Pyrrolopyrazine kinase inhibitors |
February 21, 2012 |
| The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, ##STR00001## wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| 8008298 |
Pyrrolopyrazine kinase inhibitors |
August 30, 2011 |
| The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, ##STR00001## wherein the variables Q.sup.1, R, and X are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| 7943618 |
Btk protein kinase inhibitors |
May 17, 2011 |
| This application discloses pyridine and pyrimidine compounds according to formula I wherein R.sup.1, ##STR00001## R.sup.2, R.sup.3, R.sup.4, R.sup.5, X.sup.1 and A are as described herein which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and |
| 7939531 |
Pyrrolopyrazine kinase inhibitors |
May 10, 2011 |
| The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, ##STR00001## wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| 7932254 |
Pyrrolopyrazine kinase inhibitors |
April 26, 2011 |
| The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, ##STR00001## wherein the variables Q.sup.1 and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| 7906509 |
Inhibitors of bruton's tyrosine kinase |
March 15, 2011 |
| This application discloses 5-phenyl-1H-pyridin-2-one and 6-phenyl-2H-pyridazin-3-one derivatives according to generic Formulae I-III: ##STR00001## wherein, variables R, X, Y.sup.1, Y.sup.2, Y.sup.3, Y.sup.4, n and m are defined as described herein, which inhibit Btk. The compounds d |
| 7902197 |
Pyrrolopyrazine kinase inhibitors |
March 8, 2011 |
| The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, ##STR00001## wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases. |
| 7902194 |
Inhibitors of bruton's tyrosine kinase |
March 8, 2011 |
| This application discloses 5-phenyl-1H-pyridin-2-one and 6-phenyl-2H-pyridazin-3-one derivatives according to generic Formulae I-IV: ##STR00001## wherein, variables R, X, Y.sup.1, Y.sup.2, Y.sup.2, Y.sup.3, Y.sup.4, n and m are defined as described herein, which inhibit Btk. The com |
| 7683064 |
Inhibitors of Bruton's tyrosine kinase |
March 23, 2010 |
| This application discloses 5-phenyl-1H-pyridin-2-one and 6-phenyl-2H-pyridazin-3-one derivatives according to generic Formulae I-III: ##STR00001## wherein, variables R, X, Y.sup.1, Y.sup.2, Y.sup.3, Y.sup.4, n and m are defined as described herein, which inhibit Btk. The compounds d |
| 7563800 |
Substituted pyrazolo[3,4-D]pyrimidines as p38 map kinase inhibitors |
July 21, 2009 |
| Compounds of formula Ia or Ib: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein. Also disclosed are methods of making the compounds and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases. |
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