| |
 |
|
|
Inventor: Loffler; Bernd-Michael
Address: Oberrimsingen, DE
No. of patents: 8
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| 6133442 |
Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antago |
October 17, 2000 |
| Compounds of formula I ##STR1## wherein R.sup.1 signifies phenyl, substituted phenyl or heterocyclyl;R.sup.2 signifies phenyl or substituted phenyl;R.sup.3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, substituted phenyl, heterocyclyl or a residue --CON |
| 6004965 |
Sulfonamides |
December 21, 1999 |
| Compounds of the formula: ##STR1## where A, B, R.sup.1 -R.sup.8 are as described herein are endothelin inhibitors that can be used in treating diseases associated with endothelin, such as high blood pressure. Chemical synthesis of these compounds and pharmaceutical compositions c |
| 5962682 |
Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antagon |
October 5, 1999 |
| Compounds of formula (I) ##STR1## wherein R.sup.1 signifies phenyl, substituted phenyl or heterocyclyl; R.sup.2 signifies phenyl or substituted phenyl; R.sup.3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, substituted phenyl, heterocyclyl or a resid |
| 5856484 |
Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity |
January 5, 1999 |
| Compounds of formula I: ##STR1## are disclosed. The compounds inhibit the binding of endothelin to its receptors. |
| 5837708 |
Sulphonamides |
November 17, 1998 |
| Compounds of the formula ##STR1## wherein the variables are hereinbelow defined. The compounds of formula I are inhibitors for endothelin receptors. They can be used for the treatment of disorders which are associated with endothelin activities, especially circulatory disorders s |
| 5541186 |
Sulfonylaminopyrimidines |
July 30, 1996 |
| A compound of the formula ##STR1## wherein R.sup.1 to R, R.sup.a, R.sup.b X, Y, Z, m and n have the significance given in the description, can be used as medicaments, especially for the treatment and prophylaxix of conditions which are associated with endothelin activities. |
| 5420129 |
Phenylsulfonylamide pyrimidine |
May 30, 1995 |
| The invention is concerned with novel sulphonamides and their use as medicaments. In particular, the invention is concerned with compounds of the formula ##STR1## wherein R.sup.1 is hydrogen, lower-alkyl, lower-alkoxy, lower-alkylthio, halogen or trifluoromethyl;R.sup.2 is hydrog |
| 5292740 |
Sulfonamides |
March 8, 1994 |
| The novel sulfonamides of formula I, ##STR1## in which the symbols R.sup.1 -R.sup.9, R.sup.a, R.sup.b, X, Y and n have the significance given in the description and salts thereof can be used for the treatment of circulatory disorders, especially hypertension, ischemia, vasopasms |
|
|
|
