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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Lobb; Roy R.
Address:
Westwood, MA
No. of patents:
14
Patents:












Patent Number Title Of Patent Date Issued
8226950 Recombinant anti-VLA4 antibody molecules July 24, 2012
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi
7829092 Recombinant anti-VLA4 antibody molecules November 9, 2010
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi
7482003 Treatment for asthma with .alpha.4-specific antibodies January 27, 2009
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi
7176184 Treatment for inflammatory bowel disease with a fibronectin polypeptide February 13, 2007
A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a surface molecule expressed on most types of white blood cells and involved in leukocyte adhesion to endo
7157086 Treatment for inflammatory bowel disease with .alpha.4-specific antibodies January 2, 2007
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi
6602503 Recombinant anti-VLA-4 antibody molecules August 5, 2003
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi
6482409 Treatment for inflammatory bowel disease with a vcam-1/1gG fusion protein November 19, 2002
A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of a VCAM-1/IgG fusion protein.
6307025 VCAM fusion proteins and DNA coding therefor October 23, 2001
VCAM fusion proteins capable of binding to VLA4, and DNA molecules coding on these fusions.
6252043 Vascular cell adhesion molecule (VCAM) polypeptides June 26, 2001
VCAM1 polypeptides and VCAM11/ICAM fusion proteins are disclosed.
5932214 Treatment for inflammatory bowel disease with VLA-4 blockers August 3, 1999
A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a surface molecule expressed on most types of white blood cells and involved in leukocyte adhesion to endo
5871734 Treatment for asthma with VLA-4 blocking agents February 16, 1999
A method for the treatment of asthma is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a protein expressed on the surface of certain leukocytes such as eosinophils.
5367056 Endothelial cell-leukocyte adhesion molecules (ELAMs) and molecules involved in leukocyte adhesi November 22, 1994
DNA sequences encoding endothelial cell-leukocyte adhesion molecules ELAMs, methods for producing such molecules, and ELAMs (including the specific molecules ELAM1 and VLAM1 and 1b) essentially free of normally associated animal proteins are disclosed.DNA sequences encoding molecules inv
5272263 DNA sequences encoding vascular cell adhesion molecules (VCAMS) December 21, 1993
DNA sequences encoding vascular cell adhesion molecules 1 and 1b ("VCAM1" and "VCAM1B"), recombinant DNA molecules comprising those sequences, and unicellular hosts transformed with those recombinant DNA molecules.
5217870 Monoclonal antibodies against CDX June 8, 1993
Monoclonal antibodies against CDX, a leukocyte cell surface molecule that is a ligand of ELAM 1, and methods for producing them. Monoclonal antibody SGB.sub.3 B.sub.4 and monoclonal antibodies reactive to the same epitope. These monoclonal antibodies inhibit leukocyte-endothelial cell ad










 
 
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