| Patent Number |
Title Of Patent |
Date Issued |
| 8226950 |
Recombinant anti-VLA4 antibody molecules |
July 24, 2012 |
| The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi |
| 7829092 |
Recombinant anti-VLA4 antibody molecules |
November 9, 2010 |
| The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi |
| 7482003 |
Treatment for asthma with .alpha.4-specific antibodies |
January 27, 2009 |
| The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi |
| 7176184 |
Treatment for inflammatory bowel disease with a fibronectin polypeptide |
February 13, 2007 |
| A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a surface molecule expressed on most types of white blood cells and involved in leukocyte adhesion to endo |
| 7157086 |
Treatment for inflammatory bowel disease with .alpha.4-specific antibodies |
January 2, 2007 |
| The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi |
| 6602503 |
Recombinant anti-VLA-4 antibody molecules |
August 5, 2003 |
| The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In additi |
| 6482409 |
Treatment for inflammatory bowel disease with a vcam-1/1gG fusion protein |
November 19, 2002 |
| A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of a VCAM-1/IgG fusion protein. |
| 6307025 |
VCAM fusion proteins and DNA coding therefor |
October 23, 2001 |
| VCAM fusion proteins capable of binding to VLA4, and DNA molecules coding on these fusions. |
| 6252043 |
Vascular cell adhesion molecule (VCAM) polypeptides |
June 26, 2001 |
| VCAM1 polypeptides and VCAM11/ICAM fusion proteins are disclosed. |
| 5932214 |
Treatment for inflammatory bowel disease with VLA-4 blockers |
August 3, 1999 |
| A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a surface molecule expressed on most types of white blood cells and involved in leukocyte adhesion to endo |
| 5871734 |
Treatment for asthma with VLA-4 blocking agents |
February 16, 1999 |
| A method for the treatment of asthma is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a protein expressed on the surface of certain leukocytes such as eosinophils. |
| 5367056 |
Endothelial cell-leukocyte adhesion molecules (ELAMs) and molecules involved in leukocyte adhesi |
November 22, 1994 |
| DNA sequences encoding endothelial cell-leukocyte adhesion molecules ELAMs, methods for producing such molecules, and ELAMs (including the specific molecules ELAM1 and VLAM1 and 1b) essentially free of normally associated animal proteins are disclosed.DNA sequences encoding molecules inv |
| 5272263 |
DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
December 21, 1993 |
| DNA sequences encoding vascular cell adhesion molecules 1 and 1b ("VCAM1" and "VCAM1B"), recombinant DNA molecules comprising those sequences, and unicellular hosts transformed with those recombinant DNA molecules. |
| 5217870 |
Monoclonal antibodies against CDX |
June 8, 1993 |
| Monoclonal antibodies against CDX, a leukocyte cell surface molecule that is a ligand of ELAM 1, and methods for producing them. Monoclonal antibody SGB.sub.3 B.sub.4 and monoclonal antibodies reactive to the same epitope. These monoclonal antibodies inhibit leukocyte-endothelial cell ad |
