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Inventor:
Liu; Huaqing
Address:
Buffalo Grove, IL
No. of patents:
9
Patents:




Patent Number Title Of Patent Date Issued
7553964 Cyclobutyl amine derivatives June 30, 2009
Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions
7456196 Bicyclic-substituted amines as histamine-3 receptor ligands November 25, 2008
Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions
7205316 Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands April 17, 2007
Compounds of formula (I) ##STR00001## wherein R.sub.1 or R.sub.2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R.sub.1, R.sub.2, R.sub.3, R.sub.3a, R.sub.3b, R.sub.4, R.sub.5, L, X, X', Y, Y', Z, and Z' are as defined herein, are useful in tre
7153889 Bicyclic-substituted amines as histamine-3 receptor ligands December 26, 2006
Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions
7115591 Prostaglandin endoperoxide H synthase biosynthesis inhibitors October 3, 2006
The present invention describes pyridazinone compounds of formula I ##STR00001## which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2), COX-2 is the inducible isoform associated with inflammation, as opposed to the constit
7098222 Bicyclic-substituted amines having cyclic-substituted monocyclic substituents August 29, 2006
Compounds of formula (I) ##STR00001## wherein R.sub.1 or R.sub.2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L.sub.2 and L.sub.3, to a heteroaromatic core, and X, X', Y, Y', Z, Z', R.sub.1, R.sub.2, R.sub.3, R.sub.3a, R.sub.3b, R.sub.4,
7001895 Prostaglandin endoperoxide H synthase biosynthesis inhibitors February 21, 2006
The present invention describes pyridazinone compounds of formula I ##STR00001## which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constit
6559140 Cyclic and bicyclic diamino histamine-3 receptor antagonists May 6, 2003
Compounds of formula (I) ##STR1##compounds of formula (II) ##STR2##compounds of formula (III) ##STR3##andcompounds of formula (IV) ##STR4##or pharmaceutically acceptable salts thereof are useful as H.sub.3 receptor antagonists. Processes to make the compounds and methods of treat
6307047 Prostaglandin endoperoxide H synthase biosynthesis inhibitors October 23, 2001
The present invention describes pyridazinone compounds of formula I ##STR1##which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isof


 
 
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