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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Le; Thuy X. H.
Address:
Monmouth Junction, NJ
No. of patents:
9
Patents:












Patent Number Title Of Patent Date Issued
8278334 Cyclic amine BACE-1 inhibitors having a benzamide substituent October 2, 2012
Disclosed are compounds of the formula ##STR00001## or a pharmaceutically acceptable salt or solvate thereof, wherein R.sup.1 is ##STR00002## R is --C(O)--N(R.sup.27)(R.sup.28) or ##STR00003## and the remaining variables are as defined in the specification. Also disclose
8242112 Heterocyclic aspartyl protease inhibitors August 14, 2012
Disclosed are compounds of the formula I ##STR00001## or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, --C(.dbd.S)--, --S(O)--, --S(O).sub.2--, --C(.dbd.O)--, --O--, --C(R.sup.6)(R.sup.7)--, --N(R.sup.5)-- or --C(.dbd.N(R.s
8178513 Heterocyclic aspartyl protease inhibitors May 15, 2012
Disclosed are compounds of the formula I ##STR00001## or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W, U, X, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as defined herein, and pharmaceutical compositions comprising the compounds of form
7973067 Heterocyclic aspartyl protease inhibitors July 5, 2011
Disclosed are compounds of the formula I ##STR00001## or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, --C(.dbd.S)--, --S(O)--, --S(O).sub.2--, --C(.dbd.O)--, --O--, --C(R.sup.6)(R.sup.7)--, --N(R.sup.5)-- or --C(.dbd.N(R.s
7759353 Substituted spiro iminopyrimidinones as aspartyl protease inhibitors, compositions, and methods July 20, 2010
Disclosed are certain substituted spiro iminopyrimidinones and other compounds of the formula I ##STR00001## or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein U, W, A, R, R.sup.1, R.sup.2, R.sup.6a and R.sup.7, are as defined in the specifi
7700603 Heterocyclic aspartyl protease inhibitors April 20, 2010
Disclosed are compounds of the formula I ##STR00001## or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, --C(.dbd.S)--, --S(O)--, --S(O).sub.2--, --C(.dbd.O)--, --O--, --C(R.sup.6)(R.sup.7)--, --N(R.sup.5)-- or --C(.dbd.N(R.sup.5)
7662816 Cyclic amine BACE-1 inhibitors having a benzamide substituent February 16, 2010
Disclosed are compounds of the formula ##STR00001## or a pharmaceutically acceptable salt or solvate thereof, wherein R.sup.1 is ##STR00002## R is --C(O)--N(R.sup.27)(R.sup.28) or ##STR00003## and the remaining variables are as defined in the specification.Also disclosed are
7598250 Cyclic amine BACE-1 inhibitors having a heterocyclic substituent October 6, 2009
Disclosed are novel compounds of the formula ##STR00001## or a pharmaceutically acceptable salt or solvate thereof, wherein R.sup.1 is ##STR00002## X is --O--, --C(R.sup.14).sub.2-- or --N(R)--; Z is --C(R.sup.14).sub.2-- or --N(R)--; t is 0, 1, 2 or 3; each R and R.sup.2 is
7592348 Heterocyclic aspartyl protease inhibitors September 22, 2009
Disclosed are compounds of the formula I ##STR00001## or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, --C(.dbd.S)--, --S(O)--, --S(O).sub.2--, --C(.dbd.O)--, --O--, --C(R.sup.6)(R.sup.7)--, --N(R.sup.5)-- or --C(.dbd.N(R.sup.5)










 
 
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