| Patent Number |
Title Of Patent |
Date Issued |
| 6583126 |
Phosphonic acid derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B) |
June 24, 2003 |
| The invention encompasses the novel class of compounds represented by formula I which are inhibitors of the PTP-1B enzyme. ##STR1##The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, a |
| 6498151 |
Aryldifluoromethylphosphonic acids with sulfur-containing substituents as PTP-1B inhibitors |
December 24, 2002 |
| The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. ##STR1##The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes. |
| 6486142 |
Phosphonic acid derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B) |
November 26, 2002 |
| The invention encompasses the novel class of compounds represented by formula I, which are inhibitors of the PTP-1B enzyme. ##STR1##The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, |
| 6486141 |
Phosphonic acid biaryl derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B) |
November 26, 2002 |
| The invention encompasses the novel class of compounds represented by formula I which are inhibitors of the PTP-1B enzyme. ##STR1##The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, a |
| 6465509 |
Pyrones as inhibitors of cyclooxygenase-2 |
October 15, 2002 |
| The invention encompasses the novel compounds of Formula I, which are useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##The invention also encompasses certain pharmaceutical compositions comprising compounds of Formula I as well as methods of treating cyclooxygen |
| 6169188 |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors |
January 2, 2001 |
| The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I. |
| 6020343 |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors |
February 1, 2000 |
| The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula |
| 5981576 |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors |
November 9, 1999 |
| The invention encompasses the novel compound of Formula A that is useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of |
| 5677318 |
Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents |
October 14, 1997 |
| The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. ##STR1## The invention al |
| 5639780 |
N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors |
June 17, 1997 |
| The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula |
