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Inventor:
Kuo; Gee-Hong
Address:
Scotch Plains, NJ
No. of patents:
32
Patents:












Patent Number Title Of Patent Date Issued
8258177 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs September 4, 2012
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
8242173 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs August 14, 2012
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
8106095 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs January 31, 2012
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
8012963 3,4-dihydro-2H-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors September 6, 2011
The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
8008513 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs August 30, 2011
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
7928238 1,2,3,4-tetrahydro-quinoline derivatives as CETP inhibitors April 19, 2011
The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
7875744 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs January 25, 2011
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
7812053 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs October 12, 2010
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
7786135 Substituted pyrroline kinase inhibitors August 31, 2010
The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
7781450 Substituted pyrroline kinase inhibitors August 24, 2010
The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
7750048 GPR40 agonists July 6, 2010
The invention is directed to compounds of Formula (I) useful as GPR40 agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, insulin resistance, hyperglycemia, obesity, diabetes such as NIDDM, and other disorders related to
7749995 3,4-dihydro-2h-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors July 6, 2010
The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
7705015 Substituted pyrroline kinase inhibitors April 27, 2010
The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
7678786 Benzoazepin-oxy-acetic acid derivatives as PPAR-delta agonists used for the increase of HDL-C, l March 16, 2010
The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia,
7635718 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs December 22, 2009
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
7598416 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs October 6, 2009
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
7598292 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs October 6, 2009
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
7524858 Substituted pyrroline kinase inhibitors April 28, 2009
The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
7498351 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs March 3, 2009
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
7425649 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs September 16, 2008
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
7301050 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs November 27, 2007
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
7205298 Substituted triazine kinase inhibitors April 17, 2007
The present invention provides substituted 1,3,5-triazine compounds as kinase inhibitors and a method for treating or ameliorating a kinase mediated disorder.
7125878 Substituted pyrroline kinase inhibitors October 24, 2006
The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder.
7015329 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs March 21, 2006
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
6841682 Heterocycles useful in the treatment of benign prostatic hyperplasia January 11, 2005
This invention relates a to a series of heterocyclic substituted piperazines of Formula I ##STR1##pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the .alpha.-1a adrenergic receptor,
6828327 Macroheterocylic compounds useful as kinase inhibitors December 7, 2004
This invention is directed to macroheterocyclic compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder.
6780994 Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia August 24, 2004
This invention relates to a series of heterocyclic substituted piperazines of Formula I ##STR1##pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the .alpha.-1.sub.a adrenergic recept
6710048 Pyrazine derivatives as modulators of tyrosine kinases March 23, 2004
The present invention provides pyrazine derivatives that inhibit tyrosine kinase activity. Certain pyrazine derivatives are selective inhibitors of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. The present invention also provides pharmaceutical formulations containi
6384035 Heterocycles useful in the treatment of benign prostatic hyperplasia May 7, 2002
This invention relates a to a series of heterocyclic substituted piperazines of Formula I ##STR1##pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the .alpha.-1a adrenergic receptor,
6362338 Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia March 26, 2002
This invention relates to a series of substituted piperazines of Formula II, as well as enantiomers thereof ##STR1##These compounds are useful in the manufacture of pharmaceutical compositions.
6218396 Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia April 17, 2001
This invention relates a to a series of heterocyclic substituted piperazines of Formula I ##STR1##methods of treatment, pharmaceutical compositions containing them, and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the .alpha.-
6063785 Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia May 16, 2000
This invention relates to a series of heterocyclic substituted piperazines of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the (.alpha.-1.sub.a adrenergic










 
 
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