| Patent Number |
Title Of Patent |
Date Issued |
| 7619081 |
siRNA targeting coatomer protein complex, subunit beta 2 (COPB2) |
November 17, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7615541 |
siRNA targeting TIE-2 |
November 10, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7612196 |
siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) |
November 3, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7608707 |
siRNA targeting survivin |
October 27, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. |
| 7608706 |
siRNA targeting ras-related nuclear protein |
October 27, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7605252 |
siRNA targeting kinase insert domain receptor (KDR) |
October 20, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7605250 |
siRNA targeting cAMP-specific phosphodiesterase 4D |
October 20, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7598370 |
siRNA targeting polo-like kinase-1 (PLK-1) |
October 6, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7598369 |
siRNA targeting histamine receptor H1 |
October 6, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7595389 |
siRNA targeting casitas B cell lymphoma-B (CBL-B) |
September 29, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7595388 |
siRNA targeting EPH receptor A3 (EPHA3) |
September 29, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7595387 |
Modified polynucleotides for reducing off-target effects in RNA interference |
September 29, 2009 |
| Methods and compositions for performing RNA interference with decreased off-target effects are provided The methods and compositions permit effective and efficient applications of RNA interference to applications such as diagnostics and therapeutics through the use of modifications to |
| 7592444 |
siRNA targeting myeloid cell leukemia sequence 1 |
September 22, 2009 |
| Efficient sequence specific gene silencing of myeloid cell leukemia sequence 1 is possible through the use of siRNA technology. By selecting particular siRNAs directed to myeloid cell leukemia sequence 1 by rationale design, one can maximize the generation of an effective gene silenc |
| 7592443 |
siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4) |
September 22, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7592442 |
siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2) |
September 22, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7589191 |
siRNA targeting hypoxia-inducible factor 1 |
September 15, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7582747 |
siRNA targeting inner centromere protein antigens (INCENP) |
September 1, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7582746 |
siRNA targeting complement component 3 (C3) |
September 1, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7579458 |
siRNA targeting synuclein, alpha (SNCA-1) |
August 25, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7579457 |
siRNA targeting carbonic anhydrase II |
August 25, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. |
| 7576197 |
SiRNA targeting KRAS |
August 18, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs directed to silencing KRAS, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. |
| 7576196 |
siRNA targeting transducin (beta)-like 3 (TBL3) |
August 18, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7569684 |
siRNA targeting gremlin |
August 4, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7550572 |
siRNA targeting cell division cycle 20 homolog (CDC20) |
June 23, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7541453 |
siRNA targeting aquaporin 4 |
June 2, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7521191 |
siRNA targeting connexin 43 |
April 21, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits |
| 7514550 |
siRNA targeting myeloid cell leukemia sequence 1 |
April 7, 2009 |
| Efficient sequence specific gene silencing of myeloid cell leukemia sequence 1 is possible through the use of siRNA technology. By selecting particular siRNAs directed to myeloid cell leukemia sequence 1 by rationale design, one can maximize the generation of an effective gene silenc |
| 7511132 |
Functional and hyperfunctional siRNA directed against Bcl-2 |
March 31, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing Bcl-2. |
| 7507811 |
siRNA targeting KRAS |
March 24, 2009 |
| Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. |
| 6225063 |
RNA channels in biological membranes |
May 1, 2001 |
| The present invention provides nucleic acid molecules capable of binding phospholipid membranes, and more particularly RNA molecules capable of binding and forming channels in biological membranes. In this regard the present invention provides methods for screening nucleic acid molecules |
