| Patent Number |
Title Of Patent |
Date Issued |
| 7585968 |
Compositions and their uses directed to thymus and activation-regulated chemokine (TARC) |
September 8, 2009 |
| Disclosed herein are compounds, compositions and methods for modulating the expression of TARC in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment |
| 7507810 |
Compositions and their uses directed to IL-4R alpha |
March 24, 2009 |
| Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for tre |
| 7307069 |
Antisense oligonucleotide modulation of STAT3 expression |
December 11, 2007 |
| Compounds, compositions and methods are provided for inhibiting the expression of human STAT3. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding STAT3. Methods of using these oligonucleotides for inhibition of STAT3 expression and for promotion o |
| 7235653 |
Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
June 26, 2007 |
| Compositions and methods for the treatment of asthma with oligonucleotides which specifically hybridize with nucleic acids encoding B7 proteins. |
| 7115580 |
Antisense modulation of B7 protein expression |
October 3, 2006 |
| Compositions and methods for the diagnosis, prevention and treatment of immune states and disorders amenable to treatment through modulation of T cell activation are provided. In accordance with preferred embodiments, oligonucleotides are provided which are specifically hybridizable with |
| 7098192 |
Antisense oligonucleotide modulation of STAT3 expression |
August 29, 2006 |
| Compounds, compositions and methods are provided for inhibiting the expression of human STAT3. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding STAT3. Methods of using these oligonucleotides for inhibition of STAT3 expression and for promotion o |
| 6727064 |
Antisense oligonucleotide modulation of STAT3 expression |
April 27, 2004 |
| Compounds, compositions and methods are provided for inhibiting the expression of human STAT3. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding STAT3. Methods of using these oligonucleotides for inhibition of STAT3 expression and for promotion o |
| 6210892 |
Alteration of cellular behavior by antisense modulation of mRNA processing |
April 3, 2001 |
| The present invention provides compositions and methods for controlling the behavior of a cell, tissue or organism through antisense modulation of mRNA processing, using antisense compounds which does not support cleavage of the mRNA target. |
| 6159694 |
Antisense modulation of stat3 expression |
December 12, 2000 |
| Compounds, compositions and methods are provided for inhibiting the expression of human STAT3. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding STAT3. Methods of using these oligonucleotides for inhibition of STAT3 expression and for treatment o |
| 6136603 |
Antisense modulation of interleukin-5 signal transduction |
October 24, 2000 |
| Compositions and methods are provided for antisense modulation of interleukin-5 signal transduction. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding interleukin-5 and interleukin-5 receptor.alpha. are preferred. Methods of using these |
