| Patent Number |
Title Of Patent |
Date Issued |
| 7122519 |
Didemnin analogs and fragments and methods of making and using them |
October 17, 2006 |
| The present invention relates to macrocyclic depsipeptides, including didemnin analogs and fragments thereof, which are useful as anti-cancer agents and for other purposes. The invention includes numerous didemnin analogs and fragments and methods of making them. Methods of using these |
| 7064105 |
Deoxo-proline-containing tamandarin and didemnin analogs, dehydro-proline-containing tamandarin |
June 20, 2006 |
| The present invention relates to tamandarin and didemnin analogs which have a deoxo-proline residue or a dehydro-proline residue in their structure. These analogs are useful as anti-cancer agents and for other purposes. Methods of making these analogs and methods of using them as inh |
| 6569848 |
Compounds for the treatment of alzheimer's disease |
May 27, 2003 |
| The present invention is directed to analogs of galanthamine of the structure ##STR1##wherein the R terms are herein defined, for use in treating Alzheimer's disease. |
| 6509315 |
Didemnin analogs and fragments and methods of making and using them |
January 21, 2003 |
| The present invention relates to macrocyclic depsipeptides, including didemnin analogs and fragments thereof, which are useful as anti-cancer agents and for other purposes. The invention includes numerous didemnin analogs and fragments and methods of making them. Methods of using these |
| 6319919 |
Galanthamine derivatives for treatment of alzheimer's disease |
November 20, 2001 |
| Compounds of the formula ##STR1##wherein the broken line represents an optionally present double bond, and R.sub.1 -R.sub.3, R.sub.4, R.sub.6 and R.sub.9 are as defined herein, and compositions containing these compounds can be used to inhibit acetylcholinesterase activity and treat |
| 6268358 |
Compounds for the treatment of Alzheimer's disease |
July 31, 2001 |
| Analogs of galanthamine having the formula: ##STR1##wherein R.sub.1 and R.sub.2 are each independently selected from the group consisting of hydroxyl, alkoxy, aryloxy, alkyl carbonate, phenyl carbonate, benzyl carbonate, aliphatic carbamate, aryl carbamate and alkanoyloxy groups wher |
| 6150354 |
Compounds for the treatment of Alzheimer's disease |
November 21, 2000 |
| A method of treating Alzheimer's disease and related dementias by treatment with analogs of galanthamine, particularly those wherein the methoxy and hydroxy substituents are replaced by, for example carbamate groups, the methoxy is replaced by hydroxy and esters of galanthamine and O-des |
| 6127189 |
Compositions and methods for detection of an amine compound in a fingerprint |
October 3, 2000 |
| The invention includes compositions comprising and methods of using 1,2-indanedione derivatives for detecting an amine compound such as an amino acid. Methods of detecting and recording the pattern of a fingerprint on a surface are also included, as are a kit for detecting an amine c |
| 5846954 |
Cyclodextrin compounds and methods of making and use thereof |
December 8, 1998 |
| The present invention provides polyanionic, substituted CDs having cellular growth modulating-activity. The invention further provides CDs having anionic groups on one side of the CD molecule. Therapeutic methods for using, as well as methods of making the CD compounds of the invention, |
| 5760015 |
Cyclodextrin compounds and methods of making and use thereof |
June 2, 1998 |
| The present invention provides polyanionic, substituted CDs having cellular growth modulating activity. The invention further provides CDs having anionic groups on one side of the CD molecule. Therapeutic methods for using, as well as methods of making the CD compounds of the invention, |
| 5441944 |
Substituted cyclodextrin sulfates and their uses as growth modulating agents |
August 15, 1995 |
| The invention relates to highly water soluble substituted .alpha.-, .beta.- or .gamma.-cyclodextrin sulfates associated with a physiologically acceptable cation. Pathological or otherwise undesirable cell or tissue growth in mammals, including humans, is inhibited by administering theret |
