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Inventor:
Jones; Charles David
Address:
Indianapolis, IN
No. of patents:
21
Patents:












Patent Number Title Of Patent Date Issued
7772425 Vitamin D receptor modulators August 10, 2010
The present invention relates to novel, non-secosteroidal, diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
7750184 Vitamin D receptor modulators July 6, 2010
The present invention relates to novel, non-secosteroidal, sulfonate and sulfonamide functional diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease a
7601850 Phenyl-thiophene type vitamin D receptor modulators October 13, 2009
The present invention relates to novel, non-secosteroidal, phenyl-thiophene compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
7595345 Vitamin D receptor modulators September 29, 2009
The present invention relates to novel, non-secosteroidal, hydroxyl substituted, carbon-linked diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1?,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psor
7468449 Phenyl-furan compounds as vitamin D receptor modulators December 23, 2008
The present invention relates to novel, non-secosteroidal, phenyl-furan compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
7105541 Naphthyl compounds, intermediates, compositions, and methods of use September 12, 2006
The instant invention provides novel substituted naphthyl compounds, intermediates, compositions, pharmaceutical formulations, and methods of use.
6812244 Naphthyl compounds, intermediates, compositions, and methods of use November 2, 2004
The instant invention provides novel substituted naphthyl compounds, intermediates, compositions, pharmaceutical formulations, and methods of use.
6617347 Selective .beta.3 adrenergic agonists September 9, 2003
The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective .beta..sub.3 receptor agonists useful in the treatment of Type II diabetes and obesity. The invention provides
6599920 Naphthalene compounds, intermediates, formulations, and methods July 29, 2003
This invention relates to the field of pharmaceutical and organic chemistry and provides naphthalene compounds, intermediates, formulations, and methods.
6593345 Naphthyl compounds, intermediates, compositions, and methods of use July 15, 2003
The instant invention provides novel substituted naphthyl compounds, intermediates, compositions, pharmaceutical formulations, and methods of use.
6440958 Acrylic and propionic acid compounds, intermediates, processes, compositions, and methods August 27, 2002
This invention is directed to a class of acrylic and propionic acid compounds and their use in the treatment of post-menopausal symptoms and restenosis. In other embodiments, the invention is directed to intermediates and to processes for the preparation of the acrylic and propionic
6350884 Acrylic and propionic acid compounds, intermediates, processes, compositions, and method February 26, 2002
This invention is directed to a class of acrylic and propionic acid compounds and their use in the treatment of post-menopausal symptoms and restenosis. In other embodiments, the invention is directed to intermediates and to processes for the preparation of the acrylic and propionic
6232337 Selective .beta.3 adrenergic agonists May 15, 2001
The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective .beta..sub.3 receptor agonists useful in the treatment of Type II diabetes and obesity. The invention provides
6046227 Selective .beta.3 adrenergic agonists April 4, 2000
The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective .beta..sub.3 receptor agonists useful in the treatment of Type II diabetes and obesity. The invention provides
6020513 Dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods February 1, 2000
The instant invention provides dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods for use in the treatment of bone loss or bone resorption.
5994370 Indene compounds having activity as SERMS November 30, 1999
The present invention provides a class of substituted indene compounds and their pharmaceutically acceptable salts which possess selective estrogen receptor modulator (SERM) activity and are thus useful in the treatment of osteoporosis and cardiovascular disease, particularly hyperlipide
5958917 Benzofluorene compounds, intermediates, compositions, and methods September 28, 1999
The present invention provides compounds of formula I ##STR1## wherein R.sub.1 is --H, --OH, --O(C.sub.1 -C.sub.4 alkyl), --OCO(C.sub.1 -C.sub.6 alkyl), --OCOO(C.sub.1 -C.sub.6 alkyl), --OCOAr, --OCOOAr, or --OSO.sub.2 (C.sub.2 -C.sub.6 alkyl);R.sub.2 is --OH, --O(C.sub.1 -C.sub.4 al
5958916 Dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods September 28, 1999
The instant invention provides dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods for use in the treatment of bone loss or bone resorption.
5843984 Sulfated benzothiophene derivatives, methods of use and formulations containing same December 1, 1998
Sulfated benzothiophenes of the formula I ##STR1## wherein R.sup.1 is hydrogen, hydroxy, C.sub.1 -C.sub.4 alkoxy, --OCOO(C.sub.1 -C.sub.6 alkyl), --OCO(C.sub.1 -C.sub.6 alkyl), --OCOAr wherein Ar is phenyl or optionally substituted phenyl, --OSO.sub.2 (C.sub.4 -C.sub.6 straight c
5811421 Naphthyl and dihydronaphthyl intermediates, compounds, compositions, and methods September 22, 1998
The present invention provides compounds of formula ##STR1## wherein R.sup.1 is --H, --OH, --O(C.sub.1 -C.sub.4 alkyl), --OCOC.sub.6 H.sub.5, --OCO(C.sub.1 -C.sub.6 alkyl), or --OSO.sub.2 (C.sub.4 -C.sub.6 alkyl);R.sup.2 is C.sub.1 -C.sub.6 alkyl or C.sub.5 -C.sub.7 cycloalkyl which
5792762 Dihydrobenzofluorene compounds, intermediates, compositions and methods August 11, 1998
The invention provides dihydronaphthofluorene compounds, formulations, and methods of inhibiting bone loss or bone resorption, particularly osteoporosis, and cardiovascular-related pathological conditions.










 
 
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