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Inventor:
Jarvi; Esa T.
Address:
Cincinnati, OH
No. of patents:
8
Patents:












Patent Number Title Of Patent Date Issued
5877202 Indole derivatives useful to treat estrogen-related neoplasms and disorders March 2, 1999
The present invention relates to novel indole derivatives useful in down-regulating estrogen receptor expression. Also included are methods for the treatment of neoplasms or of controlling the growth of a neoplasm in a patient afflicted with a neoplastic disease, especially estrogen-
5521162 Aristeromycin analogues of 4',5'-didehydro-5'-fluoro-adenosine and methods of treating neoplasti May 28, 1996
This invention relates to certain aristeromycin/adenosine derivatives which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.
5470837 5'-vinylhalo-aristeromycin/adenosine analogs and immunosuppressants November 28, 1995
The present invention relates to a method of effecting immunosuppression in a patient in need thereof comprising administering to said patient an effective immunosuppressive amount of certain 5'-vinylhalo-aristeromycin/adenosine analogs.
5157166 Process for the preparation of di-fluro analogs of squalene October 20, 1992
This invention relates to a process for making di-fluoro analogs of squalene.
5064864 Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase November 12, 1991
This invention relates to certain novel di- and tetra-fluoro analogs of squalene and to their methods of use in lowering plasma cholesterol and in inhibiting squalene epoxidase in patients in need thereof.
5011859 Di- and tetra-fluoro analogs of squalene as inhibitors of squalene epoxidase April 30, 1991
This invention relates to certain novel di- and tetra-fluoro analogs of squalene and to their methods of use in lowering plasma cholesterol and in inhibiting squalene epoxidase in patients in need thereof.
4997925 5'-deoxy-5',5'-dihalo adenosines and purine analogues March 5, 1991
This invention relates to certain 5',5'-dihaloaristeromycin/adenosine derivatives which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.
4997924 5'-deoxy-4',5'-unsaturated-5'-substituted adenosines March 5, 1991
This invention relates to certain aristeromycin/adenosine derivatives which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.










 
 
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