| Patent Number |
Title Of Patent |
Date Issued |
| H2085 |
Penicillin binding protein from Streptococcus pneumoniae |
October 7, 2003 |
| The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzy |
| H2070 |
Streptococcus pneumoniae gene sequence for DNA ligase |
July 1, 2003 |
| The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| H2023 |
Streptococcus pneumoniae sequence GrpE |
May 7, 2002 |
| The invention provides isolated nucleic acid compounds encoding GrpE of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| H2021 |
Penicillin binding protein from Streptococcus pneumoniae |
May 7, 2002 |
| The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzy |
| 6322998 |
Recombinant DNA compounds that encode ACV synthetase activity of Cephalosporium acremonium |
November 27, 2001 |
| The present invention provides DNA compounds that encode ACV synthetase activity of Cephalosporium acremonium. The compounds can be used to construct recombinant DNA expression vectors for a wide variety of host cells, including E. coli, Penicillium, Cephalosporium, and Aspergillus. |
| 6271000 |
Streptococcus pneumoniae gene sequence mraY |
August 7, 2001 |
| The invention provides isolated nucleic acid compounds encoding enzyme mraY of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded enzyme, and a method for identifying compounds that inhibit said enzyme. |
| 6268175 |
Streptococcus pneumoniae gene sequence GCP |
July 31, 2001 |
| The invention provides isolated nucleic acid compounds encoding gcp of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| 6171834 |
Muri protein from Streptococcus pneumoniae |
January 9, 2001 |
| The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibi |
| 6162617 |
Streptococcus pneumoniae gene sequence dnaG |
December 19, 2000 |
| The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein. |
| 6143868 |
Monofunctional glycosyltransferase of Staphylococcus aureus |
November 7, 2000 |
| The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the |
| 5981281 |
Method for knockout mutagenesis in Streptococcus pneumoniae |
November 9, 1999 |
| Provided herein is a method to produce knockout mutations at targeted sites in the genome of Streptococcus pneumoniae. |
| 5948645 |
Biosynthetic gene muri from Streptococcus pneumoniae |
September 7, 1999 |
| The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibi |
| 5922540 |
Monofunctional glycosyltransferase gene of Staphylococcus aureus |
July 13, 1999 |
| The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the |
| 5834270 |
Biosynthetic gene murD from streptococcus pneumoniae |
November 10, 1998 |
| The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibi |
| 5821335 |
Biosynthetic gene murg from streptococcus pneumoniae |
October 13, 1998 |
| The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murG of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurG enzyme product and a method for identifying compounds that inhibi |
| 5789202 |
DNA encoding a novel penicillin binding protein from streptococcus pneumoniae |
August 4, 1998 |
| The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzy |
| 5710018 |
Mammalian influx peptide transporter |
January 20, 1998 |
| The present invention provides isolated DNA compounds and recombinant DNA vectors that encode mammalian influx peptide transporter activity. The invention also provides host cells transformed with these vectors and a method for production of mammalian influx peptide transporter activity |
| 5681694 |
Murd protein method and kit for identification of inhibitors |
October 28, 1997 |
| The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibi |
| 5587307 |
FemA gene of staphylococcus epidermidis, femA protein, and vectors and microorganisms comprising |
December 24, 1996 |
| The instant invention provides the femA gene of Staphylococcus epidermidis and all degenerate sequences thereof, the protein encoded by the femA gene (FemA), and vectors and microorganisms comprising genes encoding the FemA protein. |
| 5328842 |
Compounds, vectors and methods for expressing human, cytosolic phospholipase A.sub.2 |
July 12, 1994 |
| The invention includes recombinant DNA compounds, vectors and methods useful for expressing an exceptionally rare, human, cytosolic phospholipase A.sub.2 (cPLA.sub.2) enzyme. The invention also includes a method for screening compounds to identify inhibitors of cPLA.sub.2 which is be |
| 4738921 |
Derivative of the tryptophan operon for expression of fused gene products |
April 19, 1988 |
| The present invention comprises improved derivatives of the tryptophan operon useful for expressing fused gene products in E. coli and relate organism. Two of the improved derivatives disclosed are encoded on 0.43 and 0.55 kb EcoRI restriction fragments from plasmids pCZ20 and pLEBGH2 |