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Hogle; James M.
Newton, MA
No. of patents:

Patent Number Title Of Patent Date Issued
6844171 Oligomerization of hepatitis delta antigen January 18, 2005
This invention relates to HDAg peptides, including mutants, derivatives fragments and fusion molecules, including fusion proteins, coiled-coil oligomers, nucleic acid molecules, vectors comprising HDAg nucleic acid molecules, cells comprising said molecules, methods of multivalent ex
6558899 Method for identifying new anti-picornaviral compounds May 6, 2003
The present invention is broadly directed to methods of screening viral-binding compounds. In particular, the present invention provides cell-free assays to rapidly screen libraries of compounds for viral-capsid binding activity. Such compounds are useful for anti-viral treatments.
6416762 Anti-picornaviral ligands via a combinatorial computational and synthetic approach July 9, 2002
The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.g., anti-picornaviral capsid-

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