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Inventor:
Haeberli; Peter
Address:
Berthoud, CO
No. of patents:
6
Patents:




Patent Number Title Of Patent Date Issued
7553830 Compositions for the delivery of negatively charged molecules June 30, 2009
This invention features permeability enhancer molecules, and methods, to increase membrane permeability of various molecules, such as nucleic acids, polynucleotides, oligonucleotides, enzymatic nucleic acid molecules, antisense nucleic acid molecules, 2-5A antisense chimeras, triplex
7491805 Conjugates and compositions for cellular delivery February 17, 2009
This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including galactosamine and N-acetyl galactosamine derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides,
6972330 Chemical synthesis of methoxy nucleosides December 6, 2005
Process for chemical synthesis of methoxy nucleosides.
6686463 Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives February 3, 2004
The present invention provides methods for the chemical synthesis of nucleosides and derivatives thereof, including 2'-amino, 2'-N-phthaloyl, 2'-O-methyl, 2'-O-silyl, 2'-OH nucleosides, C-nucleosides, nucleoside phosphoramidites, C-nucleoside phosphoramidites, and non-nucleoside deri
6673611 Nucleic acid molecules with novel chemical compositions capable of modulating gene expression January 6, 2004
This invention relates to novel chemically-modified nucleic acid molecules having specific formulae that exhibit increased resistance to nucleases and increased binding affinity to target nucleic acid molecules. The invention further relates to methods of modulating gene expression using
6395713 Compositions for the delivery of negatively charged molecules May 28, 2002
This invention features permeability enhancer molecules, and methods, to increase membrane permeability of negatively charged polymers thereby facilitating cellular uptake of such polymers.


 
 
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