| Patent Number |
Title Of Patent |
Date Issued |
| 6617332 |
Tan-1057 derivatives |
September 9, 2003 |
| The invention relates to novel natural product derivatives of the formula (I), to processes for their preparation, to pharmaceutical compositions comprising them and to their use in the treatment of disorders in humans or animals: ##STR1##in which R.sup.1, D, X, Y and Z are defined a |
| 6069160 |
Heteroatom-containing benzocyclopentane-oxazolidinones |
May 30, 2000 |
| The invention relates to heteroatom-containing benzocyclopentaneoxazolidinones, to processes for their preparation and their use as medicaments, especially as antibacterial medicaments. |
| 5922708 |
Heteroaryl-oxazolidinones |
July 13, 1999 |
| The invention relates to novel heteroaryl-oxazolidinones of the general formula (I): ##STR1## in which the substituents are as defined in the description, to processes for their preparation and to their use as drugs, especially as antibacterial drugs. |
| 5869659 |
Heteroatom-containing cyclopentanopyridyl-oxazolidinones |
February 9, 1999 |
| The present invention relates to heteroatom-containing cyclopentanopyridyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5861413 |
2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones |
January 19, 1999 |
| The present invention relates to 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5843967 |
6-membered nitrogen-containing heteroaryl-oxazolidinones |
December 1, 1998 |
| The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5827857 |
Pyrido-fused thienyl- and furanyl-oxazolidinones |
October 27, 1998 |
| The present invention relates to new pyrido-fused thienyl- and furanyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5792765 |
Substituted oxazolidinones |
August 11, 1998 |
| The present invention relates to new substituted oxazolidinones of the general formula (1) ##STR1## in which the substituents have the meaning indicated in the description, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5698574 |
5-membered heteroaryl-oxazolidinones |
December 16, 1997 |
| The present invention relates to 5-membered heteroaryl-oxazolidinones, to processes for their preparation and to their use as medicaments, in particular as antibacterial medicaments. |
| 5684023 |
Benzofuranyl -and benzothienyloxazolidinones |
November 4, 1997 |
| The present invention relates to benzofuranyl- and benzothienyloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5646121 |
Pseudopeptides with antiviral activity |
July 8, 1997 |
| The present invention relates to novel pseudopeptides with antiviral activity of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a process for their preparation, and to their use as antiviral agents, especially against cyto |
| 5633231 |
Valine-containing pseudopeptides with antiviral activity |
May 27, 1997 |
| The present invention relates to valine-containing, substituted pseudopeptides of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to processes for their preparation, and to their use as anti-viral agents, in particular against |
| 5627181 |
6-membered nitrogen-containing heteroaryl-oxazolidinones |
May 6, 1997 |
| The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5605926 |
Trifluoromethyl-containing pseudopeptides active against retroviruses |
February 25, 1997 |
| The present invention relates to new trifluoromethyl-containing pseudopeptides of the general formula (I) ##STR1## in which W, A, B, D, E, R.sub.1, R.sub.2 and R.sub.3 have the meaning as outlined of their making and use as pharmaceuticals. |
| 5571921 |
Substituted (2-oxo-1-benzimidazolinyl)-peperidines, process for their preparation, and use as an |
November 5, 1996 |
| The present invention relates to substituted (2-oxo-1-benzimidazolinyl)-piperidines of the general formula (I) ##STR1## in which the substituents have the meaning indicated in the description, to processes for their preparation and to their use as antiretroviral agents. |
| 5529998 |
Benzoxazolyl- and benzothiazolyloxazolidinones |
June 25, 1996 |
| The invention relates to benzoxazolyl- and benzothiazolyloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments. |
| 5492918 |
Use of substituted chromans, some of which are known, as medicaments, new active compounds and p |
February 20, 1996 |
| The present invention relates to the use of substituted chromans of the general formula (I) ##STR1## in which the substituents have the meaning indicated in the description, for the production of medicaments, in particular as HIV protease-inhibiting agents, new active compounds a |
| 5492896 |
Pseudopeptides having an antiviral action |
February 20, 1996 |
| The invention relates to new pseudopeptides having an antiviral action, oft he general formula (I) ##STR1## with the meanings given in the description for the substituents, to a process for their preparation and to their use as antiviral agents, in particular against cytomegalovi |
| 5480879 |
Quinolonecarboxylic acids |
January 2, 1996 |
| The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are linked to a .beta.-lactam antibiotic, to their salts, to processes for their preparation and to antibacterial agents containing these derivatives. |
| 5430151 |
Trifluoromethyl-containing pseudopeptides active against retroviruses |
July 4, 1995 |
| The present invention relates to new trifluoromethyl-containing pseudopeptides of the general formula (I) ##STR1## in which W, A, B, D, E, R.sub.1, R.sub.2 and R.sub.3 have the meaning as outlined of their making and use as pharmaceuticals. |
| 5424426 |
Dithiolanylglycine-containing HIV protease inhibitors of the hydroxyethylene isostere type |
June 13, 1995 |
| The invention relates to dithiolanylglycine-containing HIV protease inhibitors of the hydroxyethylene isostere type of the general formula (I) ##STR1## processes for their preparation and their use as retroviral agents. |
| 5364931 |
Phosphonate-containing pseudopeptides of the hydroxyethylamine and norstatin type |
November 15, 1994 |
| The invention relates to phosphonate-containing pseudopeptides of the hydroxyethylamine and norstatin type, to new oxirane- and thiirane-containing pseudopeptides as intermediates, to processes for their preparation and to their use as retroviral agents. |
| 5204471 |
.alpha.-trifluoromethyl-substituted, saturated bicyclic amines |
April 20, 1993 |
| New .alpha.-trifluoromethyl-substituted, saturated bicyclic amines of the formula ##STR1## in which R.sup.1 represents hydrogen, C.sub.1 - to C.sub.8 -alkyl or C.sub.1 - to C.sub.8 -alkoxy,R.sup.2 represents hydrogen or C.sub.1 - to C.sub.4 -alkyl,n represents zero or 1,A represents |
| 5162538 |
Antiviral new peptides |
November 10, 1992 |
| Antiviral new peptides of the formula ##STR1## in which R.sup.3 denotes straight-chain or branched alkyl having up to 8 carbon atoms ordenotes aryl having 6 to 10 carbon atoms or tolyl, andR.sup.4 denotes straight-chain or branched alkyl having up to 8 carbon atoms,and physiologicall |
| 5147865 |
Phosphonopyrrolidine- and piperidine-containing pseudopeptides of the statin type, a process for |
September 15, 1992 |
| The invention relates to new phosphonopyrrolidine- and piperidine-containing pseudopeptides, to a process for their preparation and to their use as medicaments, in particular as antiviral agents in human and veterinary medicine. |
| 4863916 |
Substituted 6-hydroxymethyl-carbapenem antibiotics |
September 5, 1989 |
| Substituted 6-hydroxymethyl-carbapenem antibiotics of the formula ##STR1## in which R.sup.1 is --OR.sup.4, ##STR2## A is a direct bond, or an alkylene and/or cycloalkylene radical, R.sup.2 is a group of the formula ##STR3## an aryl or heterocyclic radical, ##STR4## |
| 4849531 |
Process for the preparation of 2,3-epoxyamides |
July 18, 1989 |
| A process for the preparation of a 2,3-epoxyamide of the formula ##STR1## in which R.sup.1 represents hydrogen or straight-chain or branched C.sub.1 -C.sub.8 -alkyl, which may be substituted by phenyl or halogen, or represents C.sub.3 -C.sub.7 -cycloalkyl, phenyl, C.sub.1 -C.sub.8 |
| 4841042 |
Process for the preparation of carbapenem intermediates |
June 20, 1989 |
| A process for the preparation of a 4-[3-carboxy-3-diazo-2-oxopropyl]azetidin-2-one of the formula ##STR1## comprising reacting a 4-acetoxy-2-azetininone of the formula ##STR2## with a compound of the formula ##STR3## in an inert solvent, in the presence of a base and of a |
| 4840946 |
Benzazolythio-carbapenem antibiotics |
June 20, 1989 |
| Antibiotically active benzazolylthio-carbapenems of the formula ##STR1## in which R.sup.1 represents hydrogen or a hydroxyl-protecting group,R.sup.2 represents hydrogen or a carboxyl-protecting group or an ester radical which can be cleaved off in vivo,R.sup.3 represents hydrogen or C.su |
| 4631275 |
1-Oxadethiacephalosporin derivatives and antibacterial use thereof |
December 23, 1986 |
| 1-Oxadethiacephalosporin derivatives of the formula ##STR1## in which R.sup.1 denotes hydrogen or halogen,R.sup.2 denotes hydrogen or methoxy,A is a nitrogen-containing positively charged N-containing heterocyclic 5-membered to 7-membered ring which in total can contain up to 4 heter |
| 4616084 |
Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3 |
October 7, 1986 |
| A process for the preparation of a 7-acylamino-3-hydroxy-2-cephem-4-carboxylic acid, 7-acylamino-3-hydroxy-1-dethia-1-oxa-3-cephem-4-carboxylic acid or derivative thereof of the general formula ##STR1## in which R.sup.1 is hydrogen or optionally substituted alkyl, alkenyl, al |
| 4564473 |
6-Unsubstituted-7-oxo-4-oxa-diazabicyclo(3.2.0)hept-2-ene derivatives |
January 14, 1986 |
| A compound of the formula ##STR1## in which R is hydrogen, or optionally substituted alkyl, alkenyl, alkinyl, aralkyl, aryl, heteroaryl, heteroaralkyl, aryloxyalkyl, heteroaryloxyalkyl, alkoxyalkyl, arylthioalkyl, heteroarylthioalkyl, alkylthioalkyl, alkoxy, aryloxy, alkylthio or |
| 4515789 |
.beta.-Lactam antibiotics |
May 7, 1985 |
| A 3-.beta.-(vic-dihydroxyphenylmethyleneamino-2-oxo-imidazolidine)- or 3-.beta.-(vic-dihydroxyphenyl-methyleneamino-2,3-dioxo-piperazine)-1-carbo nylamino-acetamidoazetidin-2-one having an acidic grouping on .sub.1 N, e.g. of the formula ##STR1## The compounds are antibiotically a |
| 4438114 |
.beta.-Lactam antibiotics |
March 20, 1984 |
| A .beta.-lactam of the formula ##STR1## or a hydrate thereof, in whichR represents a hydrogen atom or a methoxy group,n is 1 or 2,Z represents a group of the formula ##STR2## wherein R.sup.1 denotes an optionally substituted aryl group or an optionally substituted heterocyclyl gr |
