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Inventor:
Grundler; Gerhard
Address:
Constance, DE
No. of patents:
17
Patents:




Patent Number Title Of Patent Date Issued
7531540 Phthalazinone-piperidino-derivatives as PDE4 inhibitors May 12, 2009
The compounds of formula I ##STR00001## in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
7179810 Phthalazinone-piperidino-derivatives as PDE4 inhibitors February 20, 2007
The compounds of formula I ##STR00001## in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
7022696 Piperazino-derivatives and their use as PDE4 inhibitor April 4, 2006
The compounds of formula I ##STR00001## in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effective PDE4 inhibitors.
6953853 Phthalazinone-piperidino-derivatives as PDE4 inhibitors October 11, 2005
The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors ##STR1##
6818651 (Dihydro) isoquinoline derivatives as phosphodiesterase inhibitors November 16, 2004
3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.
6818642 Benzylaminopyrimidines November 16, 2004
Benzylaminopyrimidine compounds of a certain general formula I, in which the substituents and symbols are as defined in the description, are suitable for controlling Helicobacter bacteria.
6479514 Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity November 12, 2002
Compounds of formula (I) in which the substituents and symbols have the meanings indicated in the description, are suitable for the control of Helicobacter bacteria. ##STR1##
6395732 Pyrimidin-aminomethyl-pyridine derivatives, their preparation and their use in the control of he May 28, 2002
The present invention relates to compounds of formula (I) wherein R1, R2, and R3 are hydrogen, 1-4C-alkyl, or halogen; R4, R5, R6, and R9 are hydrogen or 1-4C-alkyl; R7 and R8 are hydrogen, 1-4C-alkyl, 1-4C-alkoxy, or halogen; A is 1-7C-alkylene, 2-7C-alkenylene, 3-7C-cycloalkylene, or
6197783 Tetrahydropyrido compounds March 6, 2001
Tetrahydropyrido compounds of formula (I) ##STR1##in which the substituents have the meanings mentioned in the description, are suitable for the prevention or treatment of gastrointestinal diseases.
6162809 Pyridylthio compounds for controlling helicobacter bacteria December 19, 2000
Pyridinylthiomethyl- and pyrimidinylthiomethyl-pyridines and their pharmacologically-acceptable compositions are useful for controlling Helicobacter bacteria and for treating those afflicted with diseases based on Helicobacter bacteria.
6124313 Imidazopyridine azolidinones September 26, 2000
Imidazopyridine-azolidinones are useful for treating or preventing amenable gastro-intestinal ailments.
6107312 Thiopyridines for use in the control of helicobacter bacteria August 22, 2000
Thiopyridines of formula (I) ##STR1## in which the substituents and symbols are as defined in the specification are suitable for use in controlling Helicobacter bacteria. They are compounded into medicament compositions and administered to subjects afflicted with a disease based
6096758 3-methylimidazopyridines August 1, 2000
The invention relates to certain substituted imidazo[1,2-a]pyridines useful in the treatment of gastro-intestinal disorders.
6043242 Imidazopyridazines March 28, 2000
Compounds of formula (I) ##STR1## in which the substituents and symbols have the meanings indicated in the description, are suitable for controlling Helicobacter bacteria.
5922720 Piperazinothiopyridines for the control of Helicobacter bacteria July 13, 1999
Compounds of formula I are piperazinothiopyridines which are useful for controlling Helicobacter bacteria. They are useful as active compounds for treating diseases based on such bacteria, and are thus useful for making appropriate medicament compositions for administering to humans affl
5859030 Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria January 12, 1999
A compound of the formula I ##STR1## Wherein all the variables are defined in the specification. The compounds are used for controlling Helicobacter bacteria.
5534515 Pyrrolopyridazines having gastrointestinal protective effects July 9, 1996
Compounds of formula (I) ##STR1## wherein R1 stands for alkyl or R5-substituted alkylene; R2 stands for alkyl; R3 stands for hydrogen, halogen, --CHO (formyl), hydroxymethyl, nitro, amino, or the substituent --CH.sub.2 O--COR7; R4 stands for halogen or the substituent --A--B--R6;


 
 
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