| Patent Number |
Title Of Patent |
Date Issued |
| 5874006 |
Aseptic collagen concentration process |
February 23, 1999 |
| A process for the aseptic concentration of collagen from about 0.25% (w/w) suspensions to gels of 15% using vortex flow filtration with a variety of membrane types--ultrafiltration and microfiltration and polymeric and stainless steel is provided. The resulting gels are suitable for use |
| 5550188 |
Polymer conjugates ophthalmic devices comprising collagen-polymer conjugates |
August 27, 1996 |
| Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type |
| 5543441 |
Implants coated with collagen-polymer conjugates |
August 6, 1996 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |
| 5523348 |
Method of preparing collagen-polymer conjugates |
June 4, 1996 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |
| 5446091 |
Collagen-polymer conjugates containing an ether linkage |
August 29, 1995 |
| Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type |
| 5413791 |
Collagen-polymer conjugates |
May 9, 1995 |
| Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type |
| 5383930 |
Method for treating fine superficial facial lines |
January 24, 1995 |
| A device for correcting fine superficial facial lines which comprises a syringe fitted with a 31-33 gauge needle and an aqueous suspension of noncrosslinked fibrillar atelopeptide collagen contained within the syringe barrel, the concentration of collagen in the suspension being in t |
| 5376375 |
Method of augmenting tissue using collagen-polymer conjugates |
December 27, 1994 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |
| 5366498 |
Device for treating fine superficial facial lines |
November 22, 1994 |
| A device for correcting fine superficial facial lines which comprises a syringe fitted with a 31-33 gauge needle and an aqueous suspension of noncrosslinked fibrillar atelopeptide collagen contained within the syringe barrel, the concentration of collagen in the suspension being in t |
| 5328955 |
Collagen-polymer conjugates |
July 12, 1994 |
| Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type |
| 5324775 |
Biologically inert, biocompatible-polymer conjugates |
June 28, 1994 |
| Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding biologically inactive, natural, biocompatible polymer to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide biocompatible conjugates. The synthet |
| 5308889 |
Dehydrated collagen-polymer strings |
May 3, 1994 |
| Medical articles in the form of strings are formed by covalently binding collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugate formulations which are extruded to make the strings. The collagen may be |
| 5306500 |
Method of augmenting tissue with collagen-polymer conjugates |
April 26, 1994 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |
| 5304595 |
Collagen-polymer conjugates |
April 19, 1994 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |
| 5264214 |
Composition for bone repair |
November 23, 1993 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |
| 5162430 |
Collagen-polymer conjugates |
November 10, 1992 |
| Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer. |