| Patent Number |
Title Of Patent |
Date Issued |
| 5962650 |
Oxygen-reduced aqueous solution of factor VIII |
October 5, 1999 |
| The present invention relates to a final drug product comprising coagulation factor VIII in an aqueous solution with a reduced concentration of oxygen. In this way, the factor VIII activity can be retained during storage to a surprisingly high degree. The factor VIII activity can be |
| 5919908 |
Protein formulation comprising coagulation factor VIII or factor IX in an aqueous solution |
July 6, 1999 |
| A final drug product comprises a plasma protein selected from the group consisting of coagulation factor VIII and factor IX, in an aqueous solution. The concentration of oxygen in the solution is reduced and/or the solution contains an antioxidant. The solution further contains a car |
| 5919766 |
Composition comprising coagulation factor VIII formulation, process for its preparation and use |
July 6, 1999 |
| The present invention relates to a novel composition comprising coagulation Factor VIII and a non-ionic surfactant such as block co-polymers, e.g. polyoxamers or polyoxyethylene (20) fatty acid esters e.g. polysorbate 20 or polysorbate 80 as a stabilizer. The composition can also compris |
| 5733873 |
Composition comprising coagulation factor VIII formulation, process for its preparation and use |
March 31, 1998 |
| A composition comprising coagulation factor VIII and a non-ionic surfactant such as block copolymers, e.g., polyoxamers or polyoxyethylene (20) sorbitan fatty acid esters, e.g., polysorbate 20 or polysorbate 80 as stabilizer is provided. The composition can also comprise sodium chloride, |
