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Inventor:
Eggenweiler; Hans Michael
Address:
Darmstadt, DE
No. of patents:
19
Patents:












Patent Number Title Of Patent Date Issued
8183279 1,3-dihydroisoindole derivatives May 22, 2012
Novel 1,3-dihydroisoindole derivatives of the formula (I), in which R.sup.1-R.sup.3 have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of
8119795 Triazole derivatives II February 21, 2012
Novel triazole derivatives of the formula (I) in which R.sup.1-R.sup.6 and Y have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 p
7989625 Thienopyridines August 2, 2011
The invention relates to novel thienopyridine derivatives of formula (I), wherein R1, R2, R3, R4 and Y have the meaning cited in claim 1, are HSP90-inhibitors and can be used for producing a medicament for treating illnesses, wherein the inhibition, regulation and/or modulation of HSP90
7977343 Adenine derivatives July 12, 2011
Novel adenine derivatives of the formula (I), in which R.sup.1, R.sup.2, R.sup.3, X and Y have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulati
7947696 2-amino-4-phenylquinazoline derivatives and the use thereof as HSP90 modulators May 24, 2011
Novel phenylquinazoline derivatives of the formula (I), in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regu
7943637 Thienopyridine derivatives and the use thereof as HSP90 modulators May 17, 2011
Novel thienopyridine derivatives of the formula (I), in which R.sup.1, R.sup.2, R.sup.3 and Y have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modu
7932401 1,5-diphenylpyrazoles April 26, 2011
Novel 1,5 diphenylpyrazole derivatives of the formula (I), in which R.sup.1-R.sup.6 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of
7906657 1,5-diphenylpyrazoles II as HSP90 inhibitors March 15, 2011
Novel 1,5-diphenylpyrazole derivatives of the formula (I) in which R.sup.1-R.sup.6 have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of H
7790723 Thiazole derivatives as phosphodiesterase IV inhibitors September 7, 2010
Thiazole derivatives of the formula I ##STR00001## in which R.sup.1, R.sup.2, R.sup.3, V, W, X and B are as defined in claim 1, act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumors, cachexia, atherosclerosis, rheumatoid arthritis, mult
7563790 Pyridazine derivatives July 21, 2009
Pyridazine derivatives of the formula (I) act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumors, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune
7544684 Hydrazono-malonitriles June 9, 2009
Hydrazono-malonitrile derivatives of the formula (I) in which R.sup.1, R.sup.2, R.sup.3, R.sup.3' and R.sup.4 have the meanings given in Claim 1 act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumors, cachexia, atherosclerosis, rheumatoid
7498334 Pyrrolopyrimidines as phosphodiesterase VII inhibitors March 3, 2009
Pyrrolopyrimidine derivatives of the formula I ##STR00001## in which R.sup.3, R.sup.4, R.sup.5, R.sup.6 and X are as defined in claim 1, act as phosphodiesterase VII inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arth
7485639 4-(benzylidene-amino)-3-(methylsulfanyl)-4h-(1,2,4)triazin-5-one derivatives having a PDE-IV inh February 3, 2009
Triazine derivatives of the formula (I) and physiologically acceptable salts and solvates thereof, in which R.sup.1, R.sup.2, A and R.sup.5 are as defined in Claim 1, exhibit phosphodiesterase IV inhibition and can be employed for the treatment of allergic diseases, asthma, chronic b
7470687 Aryl oximes December 30, 2008
Aryl oxime derivatives of the formula (I), in which R.sup.1, R.sup.2, R.sup.3, X and B are as defined in Claim 1, act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis
7312328 Benzoylpyridazines December 25, 2007
This invention relates to compounds of the formula (I) in which R.sup.1, R.sup.2, R.sup.3, X and Q are as defined above and their use as PDE IV inhibitors.
7141572 Hydrazono-malonitriles November 28, 2006
Hydrazono-malonitrile derivatives of the formula (I) in which R.sup.1, R.sup.2, R.sup.3, R.sup.3' and R.sup.4 have the meanings given in Claim 1 act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid
7135471 Aryl oximes November 14, 2006
Aryl oxime derivatives of the formula (I), in which R.sup.1, R.sup.2, R.sup.3, X and B are as defined in claim 1, act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis
7129241 Pyridazine derivatives October 31, 2006
Pyridazine derivatives of the formula (I) act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmu
6960661 [7-(3-chloro-4-methoxybenzlamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrim idin-5-ylmethoxy]acet November 1, 2005
[7-(3-chloro-4-methoxybenzylamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyri midin-5-ylmethoxy]acetic acid, ##STR1##is disclosed, as well as a process for its preperation and intermediates in the process of preparing the same.










 
 
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