| Patent Number |
Title Of Patent |
Date Issued |
| RE33125 |
3- and 5-[3-(1-arylureido)]-1,2,4-triazoles |
December 5, 1989 |
|
| 4704401 |
Substituted phenyl amidinoureas |
November 3, 1987 |
| This invention relates to a method of lowering blood pressure in humans and mammals using 2,6-disubstituted phenyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, haloacyloxy, or acyloxy group and to novel 2,6- |
| 4565826 |
Heterocyclic amidinoureas |
January 21, 1986 |
| This invention relates to a novel class of heterocyclic amidinourea and heterocyclic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparati |
| 4564640 |
Amidinoureas substituted in both the urea and amidino nitrogen positions |
January 14, 1986 |
| A method of inducing blood pressure reduction in humans and mammals by administering 2,6-disubstituted phenyl N-alkyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, acyloxy or halo acyloxy group and a novel class |
| 4515718 |
Amidinoureas |
May 7, 1985 |
| A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed. |
| 4487779 |
Substituted phenyl amidinoureas |
December 11, 1984 |
| This invention relates to a method of lowering blood pressure in humans and mammals using 2,6-disubstituted phenyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, haloacyloxy, or acyloxy group and to novel 2,6- |
| 4460585 |
1-Aryl-4-hydrazinyl-s-triazin-2-ones |
July 17, 1984 |
|
| 4452980 |
Triazinones |
June 5, 1984 |
| Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thio |
| 4443456 |
Pyridyl alkylene amidinoureas |
April 17, 1984 |
| This invention relates to a novel class of amidinourea and amidinothiourea compounds wherein the urea nitrogen atom is substituted by a heterocyclic alkylene group, and their use in pharmaceutical preparations which are useful for producing anti-ulcerogenic, antisecretory, antispasmodic, |
| 4440949 |
Amidinoureas |
April 3, 1984 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4440765 |
Amidinoureas |
April 3, 1984 |
| A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed. |
| 4436911 |
Heterocyclic amidinoureas |
March 13, 1984 |
| This invention relates to a novel class of heterocyclic amidinourea and heterocylic amidinothiourea compounds wherein the heterocyclic substitution is at the 1-N urea nitrogen atom. These compounds exhibit pharmaceutical activity and may be incorporated into pharmaceutical preparatio |
| 4418209 |
Amidinothioureas |
November 29, 1983 |
| This invention describes a new class of 1-amidino-3-phenylthiourea and N'-phenylamidinothiourea compounds wherein the phenyl group is ortho substituted, and processes for their preparation. The phenylamidinothiourea compounds may be incorporated into pharmaceutical preparations which |
| 4406897 |
6-Aryl-4-hydrazinyl-s-triazin-2-ones |
September 27, 1983 |
|
| 4393077 |
1-Methylene-1-phenylguanidine compounds |
July 12, 1983 |
| Compounds having the formula: ##STR1## wherein X.sub.1, X.sub.2, R, R.sub.1, R.sub.2 and R.sub.3 are as set forth hereinafter, their preparation and uses as ganglionic blocking agents are disclosed. |
| 4387225 |
Heterocyclic alkylene triazinones |
June 7, 1983 |
| Heterocyclic alkyl s-triazine compounds are prepared from the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give respectively substituted s-triazinones and thiones of the formula ##STR1## which have pharmacological |
| 4353842 |
Amidinoureas |
October 12, 1982 |
| A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed. |
| 4338441 |
Triazinones |
July 6, 1982 |
| Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thio |
| 4304786 |
Amidinoureas |
December 8, 1981 |
| A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed. |
| 4298608 |
Method for blocking high frequency nerve stimulation |
November 3, 1981 |
| 1,4-Disubstituted-1,2-dihydro-1,3,5-triazin-2-ones are used to block conduction of high frequency nerve impulses by selectively acting to substantially completely block high frequency impulses without significantly blocking conduction of a single impulse. The effect is reversible whe |
| 4279928 |
Method of lowering blood pressure |
July 21, 1981 |
| Multiple daily dosing with amidinoureas of the formula ##STR1## produces a significant and sustained decrease in blood pressure in humans. |
| 4267388 |
Process for producing ethynylbenzenes |
May 12, 1981 |
| There is disclosed a novel process for preparing anti-inflammatory ethynylbenzene derivatives represented by the general formula I: ##STR1## wherein Y is hydrogen, halogen or loweralkyl of 1 to 3 carbon atoms; R represents a ring having the structure: ##STR2## wherein x is 1 |
| 4246409 |
Triazinones |
January 20, 1981 |
| Novel s-triazine compounds are prepared as derivatives of the corresponding amidinourea and amidinothiourea compounds by reacting with an activated form of an acid amide to give substituted s-triazinones and thiones respectively, of the formula ##STR1## The s-triazinones and thio |
| 4242340 |
Method for the treatment of diarrheal disease conditions and symptoms in mammals |
December 30, 1980 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4242339 |
Method for treatment of gastrointestinal spasmodic disease conditions or symptoms in mammals |
December 30, 1980 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4242338 |
Method for treatment of gastrointestinal secretory and ulcerogenic disease conditions or symptom |
December 30, 1980 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4242337 |
Method for treatment of diarrheal disease conditions or symptons in mammals |
December 30, 1980 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4235929 |
Method of treatment |
November 25, 1980 |
| This invention describes a method of treating inflammation in warm blooded animals by topically administering an effective amount of benzylideneaniline or its derivatives. |
| 4230727 |
Compositions and method of treatment |
October 28, 1980 |
| Compositions for inhibiting cellular proliferation in mammals containing as the active ingredient N-benzylideneaniline and its derivatives, and the method therefor. |
| 4224340 |
Anti-inflammatory compositions containing .alpha.-phenyl-N-phenylnitrone compounds |
September 23, 1980 |
| This invention relates to novel compositions containing .alpha.-phenyl-n-phenylnitrone compounds which are useful for the topical treatment of inflammation in warm-blooded animals. |
| 4218450 |
Method for treatment of gastrointestinal spasmodic disease conditions or symptoms in mammals |
August 19, 1980 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4214003 |
Method of treatment |
July 22, 1980 |
| This invention describes a method of treating inflammation in warm-blooded animals by topically administering an effective amount of .alpha.-phenyl-N-phenylnitrone and derivatives thereof. |
| 4204000 |
Anti-ulcer amidinoureas |
May 20, 1980 |
| A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed. |
| 4203985 |
Antidiarrheal triazinones |
May 20, 1980 |
| New compositions containing as the principle active ingredient a 1,4-disubstituted-1,2-dihydro-1,3,5-triazin-2-one are used for remedial or prophylactic treatment of diarrhea and organic gastrointestinal disorders accompanied by diarrheal symptoms. |
| 4203984 |
Antisecretory triazinones |
May 20, 1980 |
| 1,4-disubstituted-1,2-dihydro-1,3,5-triazine-2-ones and their pharmaceutically acceptable salts are used in the prevention and treatment of gastrointestinal disorders associated with hyperactivity of the secretory glands in the gastrointestinal tract. |
| 4203983 |
Spasmolytic triazinones |
May 20, 1980 |
| 1,4-disubstituted-1,2-dihydro-1,3,5-triazin-2-ones and their pharmaceutically acceptable salts are used in the control of abdominal spasticity especially the treatment of spasmodic conditions of the gastrointestinal tract by administering an effective amount of the triazinone in suit |
| 4200648 |
Method of treatment |
April 29, 1980 |
| This invention describes a method of treating inflammation in warm-blooded animals by topically administering an effective amount of a benzylideneaniline derivative, and the compositions therefore. |
| 4198409 |
Triazinones for veterinary use |
April 15, 1980 |
| New compositions containing as the principle active ingredient a 1,4-disubstituted-1,2-dihydro-1,3,5-triazin-2-one are used for remedial or prophylactic treatment of diarrhea and organic gastrointestinal disorders accompanied by diarrheal symptoms. |
| 4198408 |
Method for blocking high frequency nerve stimulation |
April 15, 1980 |
| 1,4-Disubstituted-1,2-dihydro-1,3,5-triazin-2-ones are used to block conduction of high frequency nerve impulses by selectively acting to substantially completely block high frequency impulses without significantly blocking conduction of a single impulse. The effect is reversible whe |
| 4198349 |
Benzylideneaniline derivatives |
April 15, 1980 |
| This invention describes a method of treating inflammation in warm blooded animals by topically administering an effective amount of benzylideneaniline or its derivatives. |
| 4197314 |
Method of treating inflammation |
April 8, 1980 |
| Relief of inflammation and associated pain and fever by the topical administration of .alpha.-phenyl-N-phenylnitrone and its derivatives. |
| 4187317 |
Sunscreen and erythema treating with N-benzylidene anilenes |
February 5, 1980 |
| Compositions for treating radiation induced erythemas and for protecting the human skin against the harmful effects of sunlight, containing as the active ingredient N-benzylideneaniline and its derivatives. |
| 4178387 |
Method for the treatment of arrhythmia |
December 11, 1979 |
| A method for the treatment of arrhythmia by administering amidinoureas. |
| 4176198 |
Method of treatment |
November 27, 1979 |
| This invention describes a method of treating inflammation in warm blooded animals by topically administering an effective amount of benzylideneaniline or its derivatives. |
| 4169155 |
Method for treatment of gastrointestinal secretory and ulcerogenic disease conditions or symptom |
September 25, 1979 |
| A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents. |
| 4166860 |
Imidazole amidinoureas for stimulating H.sub.2 -receptors |
September 4, 1979 |
| A method of stimulating histamine H.sub.2 -receptors in mammals employing imidazole amidinoureas. |
| 4153722 |
Method of treatment |
May 8, 1979 |
| This invention describes a method of treating inflammation in warmblooded animals by topically administering an effective amount of .alpha.-phenyl-N-phenylnitrone and derivatives thereof. |
| 4152452 |
Method of topically treating inflammation |
May 1, 1979 |
| This invention describes a method of treating inflammation in warmblooded animals by topically administering an effective amount of benzylamine and its derivatives. |
| 4147804 |
Amidinourea local anesthetics |
April 3, 1979 |
| A method for producing local anesthetic action in a patient by administering amidinoureas. |
| 3976643 |
Guanidines |
August 24, 1976 |
| Novel substituted phenylquanidine compounds and processes for their preparation are disclosed. Their use as anti-hypertensive agents is also revealed. |
