| Patent Number |
Title Of Patent |
Date Issued |
| 7273861 |
Non-nucleoside reverse transcriptase inhibitors |
September 25, 2007 |
| Compounds represented by formula 1: ##STR00001## wherein R.sup.1 is H, halogen, (C.sub.1-4)alkyl, O(C.sub.1-4)alkyl, and haloalkyl; R.sup.2 is H or methyl; R.sup.3 is H or (C.sub.1-4)alkyl; R.sup.4 is H or (C.sub.1-4)alkyl; R.sup.5 is (C.sub.1-4)alkyl, (C.sub.1-4)alkyl(C.sub.3-7)cyc |
| 7105510 |
Non-nucleoside reverse transcriptase inhibitors |
September 12, 2006 |
| Compounds represented by formula I: ##STR00001## wherein R.sup.1 is H, halogen, (C.sub.1-4)alkyl, O(C.sub.1-4)alkyl, and haloalkyl; R.sup.2 is H or (C.sub.1-4)alkyl; R.sup.3 is H or (C.sub.1-4)alkyl; R.sup.4 is (C.sub.1-4)alkyl, (C.sub.1-4)alkyl(C.sub.3-7)cycloalkyl, or (C.sub.3-7)c |
| 6313095 |
Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain |
November 6, 2001 |
| Disclosed herein are tetrapeptide derivatives of the formula X--NH--CHR.sup.1 --C(W.sup.1)--NR.sup.2 --CH[CH.sub.2 C(O)--Y]--C(W.sup.2)--NH--CH[CR.sup.3 (R.sup.4)--COOH]--C(W.sup.3)--NH--CHR.sup.5 --Z wherein X is a terminal group, for example, alkanoyl or phenylalkanoyl radicals, R. |
| 5846941 |
Isosteric antiherpes peptide derivatives II |
December 8, 1998 |
| Disclosed herein are peptidomimetic compounds of the formula A--B--D--CH.sub.2 CH{CH.sub.2 C(O)R.sup.1 }C(O)--NHCH{CR.sup.2 (R.sup.3)COOH}C(O)--E wherein A is a terminal group, for example an optionally substituted phenylalkanoyl, and B is a N-methyl amino acid residue; or A and B to |
| 5830864 |
Antiherpes peptide derivatives having a ureido n-terminus |
November 3, 1998 |
| Disclosed herein are peptide derivatives of the formulawherein A is a terminal group, for example, an alkylaminocarbonyl or a phenylalkylaminocarbonyl; B is an amino acid residue; R.sup.1 is alkyl, cycloalkyl or a disubsubstituted amino; R.sup.2 is hydrogen or alkyl and R.sup.3 is alkyl, |
| 5574015 |
Isosteric antiherpes peptide derivatives |
November 12, 1996 |
| Disclosed herein are peptide derivatives of the formula A-B-D-CH.sub.2 CH{CH.sub.2 C(O)R.sup.1 }C(O)-NHCH{CR.sup.2 (R.sup.3)COOH}C(O)-E wherein A is a terminal group, for example an optionally substituted phenylalkanoyl, and B is a N-methyl amino acid residue; or A and B together form a |
| 5552384 |
Antiherpes compositions and method of use |
September 3, 1996 |
| Disclosed herein is a combination of an antiviral nucleoside analog and a ribonucleotide reductase inhibiting peptide derivative. The combination is useful for combatting herpes infections. |
| 5502036 |
Antiherpes pentapeptide derivatives having a substituted aspartic acid side chain |
March 26, 1996 |
| Disclosed herein are pentapeptide derivatives of the formula X--NR.sup.1 --CH(R.sup.2)--C(W)--NH--CR.sup.3 (R.sup.4)--C(W.sup.2)--NR.sup.5 --CH[CH.sub.2 C(O)--Y]--C(W.sup.3)--NH--CR.sup.6 --[CR.sup.7 (R.sup.8)--COOH]--C(W.sup.4)--NH--CR.sup.9 (R.sup.10)--Z wherein X is a terminal gro |
| 5484771 |
Antiherpes peptide derivatives having a 1,4-dioxo-C, N-terminus |
January 16, 1996 |
| Described herein are peptide derivatives of the formula R.sup.1 NH--CO--Q--C(O)--NR.sup.2 --CH[CH.sub.2 C(O)--Y]--C(O)--NH--CH[CR.sup.3 (R.sup.4)--COOH]--C(W)--NH--CHR.sup.5 --Z wherein R.sup.1 is an optionally substituted alkyl or optionally substituted phenylalkyl, R.sup.2 is hydro |
| 5380727 |
Synergistic combination for treating herpes infections |
January 10, 1995 |
| Disclosed herein is a combination of an antiviral nucleoside analog and a ribonucleotide reductase inhibiting peptide derivative. The combination is useful for treating herpes infections. |
