| Patent Number |
Title Of Patent |
Date Issued |
| 7576110 |
Benzothiazole cyclobutyl amine derivatives |
August 18, 2009 |
| Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions |
| 7553964 |
Cyclobutyl amine derivatives |
June 30, 2009 |
| Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions |
| 7538138 |
Amines as histamine-3 receptor ligands and their therapeutic applications |
May 26, 2009 |
| Compounds of formula (I) ##STR00001## or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the treatment of disorders ameliorated by histamine-3 receptor ligands. |
| 7470691 |
Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction |
December 30, 2008 |
| The present invention relates to the use of compounds of formula (I) ##STR00001## for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B.sub.1 are as described in the specificatio |
| 7456196 |
Bicyclic-substituted amines as histamine-3 receptor ligands |
November 25, 2008 |
| Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions |
| 7358263 |
Fused bicyclic-substituted amines as histamine-3 receptor ligands |
April 15, 2008 |
| Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositi |
| 7351828 |
Benzimidazoles that are useful in treating sexual dysfunction |
April 1, 2008 |
| The present invention relates to the use of compounds of formula (I) ##STR00001## for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction. |
| 7345034 |
Azacyclosteroid histamine-3 receptor ligands |
March 18, 2008 |
| Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein. |
| 7244852 |
Process for preparing 2-methylpyrrolidine and specific enantiomers thereof |
July 17, 2007 |
| The invention relates to a process for preparing 2-methylpyrrolidine and, more particularly, specific enantiomers of 2-methylpyrrolidine. Novel intermediates also are described. |
| 7235661 |
Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction |
June 26, 2007 |
| The present invention relates to the use of compounds of formula (I) ##STR00001## for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B.sub.1, are as described in the specificati |
| 7205316 |
Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands |
April 17, 2007 |
| Compounds of formula (I) ##STR00001## wherein R.sub.1 or R.sub.2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R.sub.1, R.sub.2, R.sub.3, R.sub.3a, R.sub.3b, R.sub.4, R.sub.5, L, X, X', Y, Y', Z, and Z' are as defined herein, are useful in tre |
| 7153889 |
Bicyclic-substituted amines as histamine-3 receptor ligands |
December 26, 2006 |
| Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions |
| 7098222 |
Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
August 29, 2006 |
| Compounds of formula (I) ##STR00001## wherein R.sub.1 or R.sub.2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L.sub.2 and L.sub.3, to a heteroaromatic core, and X, X', Y, Y', Z, Z', R.sub.1, R.sub.2, R.sub.3, R.sub.3a, R.sub.3b, R.sub.4, |
| 7094790 |
Fused bicyclic-substituted amines as histamine-3 receptor ligands |
August 22, 2006 |
| Compounds of formula (I) ##STR00001## are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositi |
| 7057042 |
Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction |
June 6, 2006 |
| The present invention relates to the use of compounds of formula (I) ##STR00001## for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B.sub.1 are as described in the specificatio |
| 7022728 |
Benzimidazoles that are useful in treating male sexual dysfunction |
April 4, 2006 |
| The present invention relates to the use of compounds of formula (I) ##STR00001## for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction. |
| 6969730 |
Amines as histamine-3 receptor ligands and their therapeutic applications |
November 29, 2005 |
| Compounds of formula (I) ##STR1##or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the treatment of disorders ameliorated by histamine-3 receptor ligands. |
| 6960589 |
Benzimidazoles that are useful in treating sexual dysfunction |
November 1, 2005 |
| The present invention relates to the use of compounds of formula (I) ##STR1##for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein L is C.sub.1-4 alkyl; R.sub.A, R.sub.B, R.sub.C, R.sub.D, and R. |
| 6822101 |
Process for preparing amine-substituted benzofurans |
November 23, 2004 |
| The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitril e, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activit |
