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Browse by: INVENTOR PATENT HOLDER PATENT NUMBER DATE
 
 
Inventor:
Clemens; Robert J.
Address:
Kingsport, TN
No. of patents:
9
Patents:












Patent Number Title Of Patent Date Issued
5693850 Nutritive water soluble glycerol esters of hydroxy butyric acid December 2, 1997
A process for the production of water soluble glycerol esters useful as parenteral nutrients is disclosed. The process comprises the reaction of glycerol or a protected glycerol and an acetoacetate ester or acetoacetate precursor, yielding an acetoacetyl glycerol which is thereafter redu
5519161 Nutritive glycerol esters of .beta.-acyloxy butyrates May 21, 1996
Novel compositions that are useful as nutrients are disclosed. These compounds are preferably water soluble parenteral nutrients and are glycerol esters of .beta.-acyloxybutyrates of the formula ##STR1## wherein each R is the same or different and is hydrogen, or --COCH.sub.2 CHO
5420335 Parenteral nutrients based on watersoluble glycerol bisacetoacetates May 30, 1995
Novel parenteral nutrient compositions are disclosed. These compositions are sterile aqueous solutions containing an effective amount of at least one glycerol bisacetoacetate of the formula: ##STR1## wherein one R group is hydrogen, and two R groups are --COCH.sub.2 COCH.sub.3).
5321118 1-acetoacetamido-2,3-propane diol monomer and polyesters prerpared therefrom June 14, 1994
Disclosed is a novel monomer composition and its preparation that is useful in the production of polyesters. This novel monomer composition is 1-acetoacetamido-2,3-propane diol and can be used in the preparation of polyesters in combination with a dicarboxylic acid.
5017649 Low temperature Michael addition reactions May 21, 1991
The condensation of .beta.-dicarbonyl compounds with .alpha.,.beta.-unsaturated compounds is promoted by amidine and guanidine compounds.
4992584 Process for the preparation of .beta.-ketocarboximides of .alpha.,.beta.-unsaturated amides February 12, 1991
A process is disclosed for the preparation of .beta.-ketocarboximides of .alpha.,.beta.-unsaturated amides from 1,3-dioxin-4-ones and .alpha.,.beta.-unsaturated amides using an inert solvent system capable of maintaining both reactants substantially in homogeneous solution throughout
4633013 Preparation of .alpha.-haloacetoacetic esters December 30, 1986
Disclosed is a process for the preparation of .alpha.-haloacetoacetic esters by the reaction of an alkali metal alkoxide with a 5-halo-4H-1,3-dioxin-4-one compound, the desired product being obtained as an alkali metal salt which may be converted to the corresponding free ester by tr
4582913 5-halo-4H-1,3-dioxin-4-one compounds April 15, 1986
Disclosed are novel 5-halo-4H-1,3-dioxin-4-ones and their preparation by treating a compound having the formula ##STR1## with X.sub.2 or SO.sub.2 X.sub.2 wherein X is Cl or Br.
4496747 Process for the preparation of dehydroacetic acid January 29, 1985
A process for the preparation of dehydroacetic acid which comprises heating 2,2,6-trimethyl-4H-1,3-dioxin-4-one, preferably at a temperature of about 130.degree. C. to about 160.degree.C., the heating being carried out preferably in the presence of an inert solvent such as xylene and










 
 
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