Patent Number |
Title Of Patent |
Date Issued |
8299072 |
Pyrazolylmethylamine compounds as calcium channel modulators and preparation method thereof |
October 30, 2012 |
The present invention relates to pyrazolylmethylamine-piperazine derivatives and their pharmaceutically acceptable salts effective as calcium channel modulators and a method of manufacturing the same. The present invention also relates to the medicinal use of the above compounds as t |
8236806 |
Piperazinyl-propyl-pyrazole derivatives as dopamine D4 receptor antagonists, and pharmaceutical |
August 7, 2012 |
The present invention relates to a novel piperazinyl-propyl-pyrazole derivative, a method of its preparation and a pharmaceutically acceptable composition comprising the same. The novel piperazinyl-propyl-pyrazole derivative of the present invention has superior selective affinity for |
8232279 |
Pyrazolopyrimidine derivatives having biological activity on serotonin receptor 5-HT2c |
July 31, 2012 |
The present invention relates to a novel medicinal use of pyrazolopyrimidine compounds having superior effect as serotonin 5-HT.sub.2C receptor ligand thus being useful for the prevention and treatment of central nervous system (CNS) diseases. Accordingly, the pharmaceutical composit |
8222257 |
Phosphono-pent-2-en-1-yl nucleosides and analogs |
July 17, 2012 |
Compounds and compositions are provided for treatment, prevention, or amelioration of a variety of medical disorders associated with viral infections and/or cell proliferation. The compounds provided herein are 5-phosphono-pent-2-en-1-yl nucleosides and esters thereof. |
8148402 |
Isoindolinone derivatives having inhibitory activity against T-type calcium channel and method f |
April 3, 2012 |
Disclosed are isoindolinone derivatives, represented by Chemical Formula 1, having inhibitory activity against T-type calcium channels, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredien |
8115019 |
Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof |
February 14, 2012 |
Disclosed are cis-2,6-disubstituted tetrahydropyran derivatives represented by Chemical Formula 1 and a preparation method thereof. The tetrahydropyran derivatives can be prepared by Prins-reacting tetrahydropyran derivatives with homopargylicalcohol derivatives in the presence of tr |
7388101 |
Tetrahydrofuran derivatives having cis substituent, their intermediates, and their preparation m |
June 17, 2008 |
The present invention relates to a tetrahydrofuran compound having cis substituents, the derivatives thereof and a process for preparing the same, and in particular relates to a dihydrofuran-3-ylidene triflate compound having cis substituents at C.sub.2 and C.sub.5 positions prepared |
7319098 |
1,3-dioxoisoindole derivatives having selective antagonism of T-type calcium channel |
January 15, 2008 |
The present invention relates to 1,3-dioxoisoindole derivatives of Formula (1) or pharmaceutically acceptable salts thereof, a preparation method thereof and use thereof as a T-type calcium channel antagonist, based on the fact that 1,3-dioxoisoindole derivatives of Formula (1) show |