| Patent Number |
Title Of Patent |
Date Issued |
| 6716964 |
CtIP, a novel protein that interacts with CtBP and uses therefor |
April 6, 2004 |
| A novel human protein, CtIP, that interacts with the human cellular protein CtBP, and the nucleotide sequence encoding CtIP are provided. CtIP is useful in diagnostic methods for determining malignancy of cells and in methods for inhibiting neoplasia in patients. Use of CtIP in a method |
| 5952179 |
Screens for mutations in the anti-proliferation domain of human Bcl-2 |
September 14, 1999 |
| A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO: 13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular |
| 5858678 |
Apoptosis-regulating proteins |
January 12, 1999 |
| Adenovirus E1B 19 kD protein protects against cell death induced by viral infection and certain external physical and chemical stimuli. Activity of the 19 kD protein is similar to the cell death suppressing activity of the protein coded by the Bcl-2 protooncogene. Bcl-2 protein can funct |
| 5821082 |
Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
October 13, 1998 |
| A domain of Bcl-2 that suppresses apoptosis by allowing cell survival permits cell proliferation when mutated. The wild type domain includes amino acid residues 51 to 97 (SEQ ID NO:13) of Bcl-2. Peptides including the domain and nucleotides encoding the domain are useful in molecular |
| 5773599 |
48 kD cellular phosphoprotein CtBP |
June 30, 1998 |
| Cloning of the cDNA for CtBP via yeast two hybrid interaction cloning. The DNA encodes a 439 amino acid (48 kD) protein that specifically interacts with exon 2. This protein requires residues 225-238 of the 243R E1A protein for interaction. The predicted protein sequence of the isolated |
