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Inventor:
Chiba; Shigeru
Address:
Kawasaki, JP
No. of patents:
13
Patents:












Patent Number Title Of Patent Date Issued
7238501 Process for producing trans-4-hydroxy-L-proline July 3, 2007
The present invention is directed to a process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is deriv
7112432 Process for producing cis-3-hydroxy-L-proline September 26, 2006
An isolated gene encodes for a L-proline-3-hydroxylase having the amino acid sequence of SEQ ID NOS: 1, 2, 15, 16 and 17, or for a protein having enzymatic activity to hydroxylate the 3-position of L-proline and to act on free L-proline in the presence of 2-ketoglutaric acid and divalent
6767726 Process for producing cis-3-hydroxy-L-proline July 27, 2004
An isolated gene encodes for a L-proline-3-hydroxylase having the amino acid sequence of SEQ ID NOS: 1, 2, 15, 16 and 17, or for a protein having enzymatic activity to hydroxylate the 3-position of L-proline and to act on free L-proline in the presence of 2-ketoglutaric acid and divalent
6642355 Endothelin-antagonizing peptide November 4, 2003
The invention relates to an endothelin antagonistic peptide of the formula (I):wherein represents Asn or Asp; B represents His or Lys; E represents Ala or Ser; G represents Ala or Pro; X represents X.sup.1 -Gly or ##STR1## and Y represents hydroxy, lower alkoxy, amino, #
6617140 Process for producing trans-4-hydroxy-L-proline September 9, 2003
Provided is an industrially applicable process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is deriv
6413748 Process for producing CIS-3-hydroxy-L-proline July 2, 2002
An industrially applicable process for producing cis-3-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into cis-3-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorgan
6242231 Process for producing trans-4-hydroxy-L-proline June 5, 2001
An industrially applicable process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is derived from a mi
6194195 Strains of streptomyces producing endothelin antagonistic peptides February 27, 2001
The invention relates to biologically pure cultures of Streptomyces sp. RE-701 (FERM BP-3624) and Streptomyces sp. RE-629 (FERM BP-4126) that produce endothelin antagonistic peptides.
6010891 Process for producing Cis-3-hydroxy-L-proline January 4, 2000
An industrially applicable process for producing cis-3-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into cis-3-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorgan
5962292 Process for producing cis-3-hydroxy-L-proline October 5, 1999
An industrially applicable process for producing cis-3-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into cis-3-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorgan
5854040 Process for producing trans-4-hydroxy-L-proline December 29, 1998
Isolated and purified L-proline-4-hydroxylase which catalyzes hydroxylation of L-proline at the 4-position of L-proline in the presence of 2-ketoglutaric acid and a divalent iron ion to produce trans-4-hydroxy-L-proline. The L-proline-4-hydroxylase may be isolated from a microorganis
5656736 Compound UCH9 August 12, 1997
The present invention relates to the compound UCH9 represented by the following formula: ##STR1## which has antibacterial and anti-tumor activity, and pharmaceutically acceptable salts thereof.
5639860 Endothelin-antagonizing peptide June 17, 1997
Peptides represented by the following formula (I): ##STR1## wherein A represents Asn or Asp; B represents His or Lys; and E represents Ala or Ser;(1) X.sup.1 and Y.sup.1 are combined together to form a single bond as X.sup.1 --Y1, or (2) X.sup.1 represents hydrogen and Y.sup.1 repres










 
 
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