| Patent Number |
Title Of Patent |
Date Issued |
| 7070777 |
Method for inhibiting inflammation with an antibody that binds the 5C8 protein |
July 4, 2006 |
| This invention provides for methods of inhibiting inflammation with antibodies that bind the 5c8 protein. |
| 6793924 |
Protein recognized by an antibody that specifically binds an epitope that is specifically bound |
September 21, 2004 |
| This invention provides a protein free of cell membranes and other cellular components, said protein being specifically recognized by an antibody that specifically binds an epitope that is specifically bound by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. H |
| 6610294 |
Methods of inhibiting an autoimmune response in a human suffering from an autoimmune disease by |
August 26, 2003 |
| This invention provides a method of inhibiting an autoimmune response in an animal suffering from an autoimmune disease selected from the group consisting of psoriasis, Lyme disease and hyper IgE syndrome which comprises administering to the animal, in an amount effective to treat the |
| 6592868 |
Methods for treating autoimmune diseases with 5C8-specific antibodies |
July 15, 2003 |
| This invention provides methods of treating autoimmune diseases, including those selected from the group consisting of rheumatoid arthritis, Myasthenia gravis, systemic lupus erythematosus, Graves' disease, idiopathic thrombocytopenia purpura, hemolytic anemia and diabetes mellitus w |
| 6570000 |
DNA encoding the T cell surface protein CD4 and use of fragments of CD4 in the treatment of AIDS |
May 27, 2003 |
| A single-stranded nucleic acid molecule which encodes an amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject |
| 6455044 |
5c8 antigen |
September 24, 2002 |
| This invention provides for an isolated protein specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention also provides for an isolated protein having substantially the same biological activity as the aforementioned is |
| 6451310 |
Method for inhibiting an allergic response with a 5c8-specific antibody |
September 17, 2002 |
| This invention provides a method of inhibiting an allergic response in a subject by inhibiting T cell activation of B cells, wherein said method comprises administering to the subject an antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5C8 |
| 6403091 |
Methods for inhibiting the rejection of a transplant organ in a subject with 5C8-specific antibo |
June 11, 2002 |
| This invention provides for a method for inhibiting rejection of a transplant organ in a subject which comprises administering to the subject an antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC |
| 6340459 |
Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of |
January 22, 2002 |
| Activation of cells bearing CD40 on their cell surface by CD40 ligand is inhibited by contacting the cells with an agent capable of inhibiting interaction between CD40 ligand and the cells, in an amount effective to inhibit activation of the cells. Activation of cells bearing CD40 on the |
| 6331615 |
Nucleic acid molecule encoding heavy or light chain of an antibody which specifically recognizes |
December 18, 2001 |
| The present invention provides for an isolated nucleic acid molecule encoding a light chain protein of an antibody, wherein the antibody binds specifically to a protein specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession Number HB 10916. The |
| 6331433 |
Human T cell leukemia cell line designated D1.1 |
December 18, 2001 |
| This invention provides for a human T cell leukemia cell line designated D1.1 having ATCC Accession No. CRL 10915. The cell line is capable of constitutively providing contact-dependent helper function to B cells. |
| 6093539 |
DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS |
July 25, 2000 |
| This invention provides an isolated single-stranded nucleic acid which encodes an aqueous-soluble polypeptide comprising at least a portion of a human T4 glycoprotein, which portion specifically forms a complex with a human immunodeficiency virus envelope glycoprotein. |
| 5993816 |
Methods to inhibit humoral immune responses, immunoglobulin production and B cell activation wit |
November 30, 1999 |
| This invention provides an isolated nucleic acid molecule encoding a protein from the surface of activated T cells, wherein the protein is necessary for T cell activation of B cells. The nucleic acid molecule may include a DNA molecule or a cDNA molecule. This invention further provides |
| 5958678 |
DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS |
September 28, 1999 |
| A single-stranded nucleic acid molecule which encodes an amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject |
| 5871913 |
DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS |
February 16, 1999 |
| A single-stranded nucleic acid molecule which encodes the amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject |
| 5788966 |
Antibody which is directed against and inhibits collagen binding to a VLA-1 epitope and uses the |
August 4, 1998 |
| The present invention provides methods of treating a subject suffering from a disorder associated with elevated levels of VLA-1 which comprises administering to the subject a therapeutically effective amount of an antibody which specifically forms a complex with VLA-1, inhibits collagen |
| 5474771 |
Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes |
December 12, 1995 |
| This invention provides a monoclonal antibody which specifically recognizes and forms a complex with a protein located on the surface of activated T cells and thereby inhibits T cell activation of B cells. This invention also provides the monoclonal antibody 5c8 (ATCC Accession No. HB 10 |
| 5391481 |
Antibody which is directed against and inhibits collagen binding to a VLA-1 epitope and uses the |
February 21, 1995 |
| The present invention provides an antibody which specifically forms a complex with and inhibits collagen binding to VLA-1 and methods of using same. |
| 5126433 |
Soluble forms of the T cell surface protein CD4 |
June 30, 1992 |
| A single-stranded nucleic acid molecule which encodes an amino acid sequence comprising at least a portion of a T4 glycoprotein is provided. Additionally, amino acid sequences which comprise at least a portion of a T4 glycoprotein and are useful as a prophylaxis for treating a subject |