| Patent Number |
Title Of Patent |
Date Issued |
| 6132987 |
Recombinant mammalian monocyte chemotactic protein-1 (MCP-1) receptors (MCP-1R, CCR-2) |
October 17, 2000 |
| DNAs encoding receptors for the chemokine, Monocyte Chemotactic Protein-1 (MCP-1), are disclosed. Recombinant reagents and methods for expressing the DNAs are also provided. Exemplary receptor proteins are MCP-1RA and MCP-1RB, which correspond to alternatively spliced transcripts of the |
| 5968902 |
Platelet aggregation inhibitors |
October 19, 1999 |
| The isolated and purified PAI from several active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K* -(G/Sar)-D wherein K* is a modified lysyl residue of the formulawherein each R.sup.1 is independently H, alky |
| 5958732 |
Platelet aggregation inhibitors |
September 28, 1999 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5935926 |
Platelet aggregation inhibitors |
August 10, 1999 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5843897 |
Platelet aggregation inhibitors |
December 1, 1998 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5807825 |
Platelet aggregation inhibitors |
September 15, 1998 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5786333 |
Platelet aggregation inhibitors |
July 28, 1998 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5770564 |
Platelet aggregation inhibitors |
June 23, 1998 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5759999 |
Platelet aggregation inhibitors |
June 2, 1998 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5756451 |
Platelet aggregation inhibitors |
May 26, 1998 |
| This invention relates to a group of peptides which are, or are related to, platelet aggregation inhibitors isolated and purified from various snake venoms. The instant platelet aggregation inhibitors inhibit (a) binding of Fg or vWF to GPIIb-IIIa more than (b) binding of vitronectin to |
| 5736339 |
Method utilizing purified GP IIb-IIIa to detect the presence of platelet aggregation inhibitors |
April 7, 1998 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5707815 |
Mammalian monocyte chemoattractant protein receptors and assays using them |
January 13, 1998 |
| Novel human chemokine receptors, MCP-1RA and MCP-1RB, and processes for producing them are disclosed. The receptors, which are alternately spliced versions of MCP-1 receptor protein may be used in an assay to identify antagonists of MCP-1 which are therapeutically useful in the treatment |
| 5705606 |
Peptides derived from GPIIIa |
January 6, 1998 |
| The present invention provides oligopeptides corresponding to regions of the GPIIIa protein, which are capable of specifically binding aggregation mediators, such as fibrinogen. The oligopeptides will typically comprise at least about 5 to 20 amino acids, and are thus non-immunogenic and |
| 5686571 |
Platelet aggregation inhibitors |
November 11, 1997 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5686570 |
Platelet aggregation inhibitors |
November 11, 1997 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5686569 |
Platelet aggregation inhibitors |
November 11, 1997 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5686568 |
Platelet aggregration inhibitors |
November 11, 1997 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5686567 |
Platelet aggregation inhibitors |
November 11, 1997 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5686566 |
Platelet aggregation inhibitors |
November 11, 1997 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5496724 |
Genes encoding platelet aggregation inhibitors |
March 5, 1996 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
| 5344783 |
Platelet aggregation inhibitors |
September 6, 1994 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of the PAI in a wide range of snake venom samples were accomplished. The |
| 5318899 |
Platelet aggregation inhibitors |
June 7, 1994 |
| An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolate |
