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Inventor:
Chance; Britton
Address:
Philadelphia, PA
No. of patents:
13
Patents:




Patent Number Title Of Patent Date Issued
6304771 Systems and methods for imaging fluorophores October 16, 2001
The systems comprise source means for illuminating the fluorophores with diffuse photon density waves of a first specified wavelength, whereby the fluorophores will fluoresce re-radiated diffuse photon density waves of a second wavelength after being illuminated with the diffuse photon d
5917190 Object imaging using diffuse light June 29, 1999
Imaging tumors using diffuse light. An imaging system includes a source of diffuse light for generating oscillatory diffuse photon density waves to illuminate an object, a detector for detecting diffuse photon density waves interacting with the object, and a computer interfaced with the
5553614 Examination of biological tissue using frequency domain spectroscopy September 10, 1996
The present invention discloses methods and apparatus for the quantitation and localization of tissue hypoxia by both time and frequency domain spectroscopy. The present invention provides several alternate embodiments of apparatus by which the saturation of a tissue region may be determ
5187672 Phase modulation spectroscopic system February 16, 1993
A phase modulated spectroscopy (PMS) system for detecting a pathophysiological condition in a subject includes two laser diodes emitting radiation at wavelengths of about 754-760 nm and 816-840 nm. These two laser diodes are modulated sinusoidally at about 220 MHz. The signals from e
5167230 User-wearable hemoglobinometer for measuring the metabolic condition of a subject December 1, 1992
A system for non-invasively determining the oxygenation state of tissue located beneath the surface of the skin, such as muscle tissue, of an exercising person or other subject is disclosed. In a preferred embodiment, a user-wearable detector array and related circuitry which use nea
5122974 Phase modulated spectrophotometry June 16, 1992
The present invention to provides methods and apparatus for studying photon migration using signal modulation techniques such as time, frequency and phase modulation. The photon migration data may then be converted, using the principles of time-resolved spectroscopy, to determine the
5081991 Methods and apparatus for using nuclear magnetic resonance to evaluate the muscle efficiency and January 21, 1992
The muscle efficiency of a subject is evaluated with apparatus comprising a nuclear magnetic resonance (NMR) analytical device which comprises a hollow electromagnet having a bore of sufficient size to receive the subject. Any type of animal can be evaluated, in a preferred embodiment a
5062428 Method and device for in vivo diagnosis detecting IR emission by body organ November 5, 1991
A sensitive photon detector can be used for external detection in vivo of emission from a body organ, for instance of singlet oxygen emission in the near infrared at 1280 nm, for various purposes such as control of oxygenation of a patient. At such a wavelength bone and overlying tissue
4981136 Nuclear magnetic resonance apparatus for evaluating muscle efficiency and maximum power of muscl January 1, 1991
The muscle efficiency of a living animal is evaluated with apparatus comprising a nuclear magnetic resonance (NMR) analytical device that comprises a hollow electromagnet having a bore of sufficient size to receive the animal. A treadmill within the bore and beneath the animal is uti
4972331 Phase modulated spectrophotometry November 20, 1990
The present invention to provides methods and apparatus for studying photon migration using signal modulation techniques such as time, frequency and phase modulation. The photon migration data may then be converted, using the principles of time-resolved spectroscopy, to determine the
4452250 NMR System for the non-invasive study of phosphorus metabilism June 5, 1984
A nuclear magnetic resonance analytic apparatus for obtaining tissue metabolism information from a living body member. The apparatus consists of a large high-intensity electromagnet with an inner space having a uniform magnetic field, for receiving the body member. The space has a pr
4162405 Flying spot fluoro-meter for oxidized flavoprotein and reduced pyridine nucleotide July 24, 1979
A method and apparatus for measuring the heterogeneity of oxygen delivery to perfused and in situ organs. A laser is employed as a flying spot scanning excitation fluorometer source which provides excitation for either oxidized flavoprotein of the mitochondrial space or reduced nucle
3963351 Multi-channel optical time-sharing apparatus having a rotating filter wheel with position-encodi June 15, 1976
A multi-wavelength time-sharing apparatus usable in various different configurations of optical measuring equipment to provide a plurality of time-shared optical channels and including appropriate circuitry. The apparatus employs a turbine-driven filter wheel having a shaft position-


 
 
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