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Inventor:
Ceriani; Roberto L.
Address:
Lafayette, CA
No. of patents:
15
Patents:












Patent Number Title Of Patent Date Issued
RE40535 Anti-KC4 humanized monoclonal antibody and cells that express the antibody October 7, 2008
An anti-KC-4 humanized monoclonal antibody that comprises the variable regions of the light and heavy chains of the anti-KC-4 murine antibody, wherein the light chain has 7 amino acids and the heavy chain has 12 amino acids of the framework regions substituted with amino acid present
6315997 Use of modified antibodies with human milk fat globule specificity November 13, 2001
An analogue peptide that comprises the variable regions of the light or heavy chains of an antibody of a first species selectively binding to a carcinoma antigen has 1 to 46 amino acids of the framework regions per chain substituted with amino acids such as those present in equivalent
6309636 Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and method October 30, 2001
The present invention provides recombinant peptides that specifically and selectively bind to the human milk fat globule (HMFG) antigen, BA46. In particular, the present invention provides recombinant variants of the Mc3 antibody, including humanized versions of Mc3. The variant Mc3 pept
6190885 Fusion protein containing HMFG Epitop E (S) February 20, 2001
A fusion protein comprises a sequence of amino acids which binds antibodies specific to the human milk fat globule (HMFG) differentiation antigens. Specific amino acid sequences are provided, and a fusion protein may be used as an immunogen and for diagnostic purposes.
5804187 Modified antibodies with human milk fat globule specificity September 8, 1998
An analogue peptide that comprises the variable regions of the light or heavy chains of an antibody of a first species selectively binding to a carcinoma antigen has 1 to 46 amino acids of the framework regions per chain substituted with amino acids such as those present in equivalent
5792852 Polynucleotides encoding modified antibodies with human milk fat globule specificity August 11, 1998
A polynucleotide encodes a modified antibody, or single chains thereof. The modified antibody has a non-antigen-binding peptide such as the constant regions of an antibody of a first species, peptide hormones, enzymes, and peptide transmitters; and a binding peptide such as the unsubstit
5766571 Method of treating human breast cancer by administration of radiolabeled antibody and unsaturate June 16, 1998
An improved in vivo method of inhibiting or retarding the growth of malignant tumor cells in a subject comprises administering the subject antitumor therapy, the improvement comprising administering to the subject at least one product comprising an agent selected from the group consi
5536647 Nucleic acids and vector encoding HMFQ polypeptide, transfected host, fusion proteins thereof, c July 16, 1996
A polypeptide has the antibody binding activity of the 70K dalton HMFG differentiation antigen and is also provided as a fusion protein with a second antigenic polypeptide. An antibody has affinity for the polypeptide of the invention or a functional fragment thereof. in vivo and in vitr
5532135 Solid-phase competitive assay utilizing a fusion protein July 2, 1996
An in vitro solid-phase, competitive assay for detecting the presence of a peptide analyte in a biological sample comprises contacting a fusion protein, of first and second peptides, with a solid supported first antibody or fragment thereof, which binds the first peptide, adding a bi
5514558 Highly sensitive and specific solid-phase competitive assay utilizing a fusion protein May 7, 1996
An in vitro solid-phase, competitive assay for detecting the presence of a peptide analyte in a biological sample, comprising contacting a fusion protein made of a first peptide and a second peptide to a solid supported first antibody which specifically binds to the first peptide, adding
5455031 Polypeptide with 46 Kdalton HMFG differentiation antigen binding specificity, composition, kit a October 3, 1995
A polypeptide has the antibody binding activity of the 46K dalton HMFG differentiation antigen and/or homology to at least one of the light chains of clotting factors V and VIII and is also provided as a fusion protein with a second antigenic polypeptide. An antibody has affinity for
5077220 Monoclonal antibody specific to a novel glycoprotein antigen on human carcinoma cells December 31, 1991
A hybridoma cell line is provided which is capable of producing monoclonal antibodies which bind to a unique determinant site on the surface and/or in the cytoplasm of human breast carcinoma cells and carcinoma cells of other adenocarcinomas and on the surface of normal human breast epit
5075219 Monoclonal antibody which recognizes a specific glycoprotein of a human milk-fat globule membran December 24, 1991
A hybridoma cell line is provided which is capable of producing a monoclonal antibody which binds to a unique determinant site on the surface and in the cytoplasm of human breast carcinoma cells and cells of other adenocarcinomas and does not bind selectively to the surface of normal
4584268 Method and compositions for carcinoma diagnosis April 22, 1986
Methods and compositions are provided for detecting the presence of carcinomas in a mammalian host by measuring the level of normal surface antigens specific for a differentiated cell in the serum of the host as compared to the normal level of such antigen. The method finds particular
4572901 Method and composition for protein immobilization February 25, 1986
Compositions, articles of manufacture, and methods are provided for enhanced binding of compounds to a surface. The compositions find particular use in coating wells, slides, other surfaces, where ligands or receptors are to be bound and detrimental non-specific binding may be encoun










 
 
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