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Inventor:
Bruce; Ian
Address:
Horsham, GB
No. of patents:
15
Patents:












Patent Number Title Of Patent Date Issued
8283362 Beta-2-adrenoreceptor agonists October 9, 2012
Compounds of formula ##STR00001## in free or salt or solvate form, where Ar is a group of formula ##STR00002## Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification,
8268834 Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme September 18, 2012
The present invention concerns a compound of formula (I) ##STR00001## or a salt, suitably a pharmaceutically acceptable salt, or solvate thereof, wherein the groups R.sup.1, R.sup.2, Ar', A and Y are defined in the description, to compositions and use of the compounds in the treatme
8263585 Organic compounds September 11, 2012
The present invention concerns a compound of formula (I) ##STR00001## or a salt, suitably a pharmaceutically acceptable salt, or solvate thereof, wherein the groups R.sup.1, R.sup.2, Ar', A and B are defined in the description, to compositions and use of the compounds in the treatme
8129541 5-phenylthiazole derivatives and use as PI3 kinase inhibitors March 6, 2012
Compounds of formula I ##STR00001## in free or salt form, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain
8067437 Beta-2-adrenoreceptor agonists November 29, 2011
Compounds of formula ##STR00001## in free or salt or solvate form, where Ar is a group of formula ##STR00002## Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification,
8053574 Organic compounds November 8, 2011
Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and use
8017608 5-Phenylthiazole derivatives and their use as p13 kinase inhibitors September 13, 2011
Compounds of formula I ##STR00001## in free or salt form, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain
7998990 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors August 16, 2011
The present invention concerns a compound of formula Ia wherein: R.sup.a* is hydrogen or C.sub.1-C.sub.4-alkyl; R.sup.b* is --(C.sub.1-C.sub.4-alkylene)-Y--C.sub.1-C.sub.4-haloalkyl or --(C.sub.1-C.sub.4-alkylene)-Y--C.sub.1-C.sub.4-hydroxyalkyl; Y represents --CONH-- or a five membe
7994203 Organic compounds August 9, 2011
There are described pyrazolo[5.1-b]oxazole derivatives useful as corticotropin releasing factor (CRF.sub.1) receptor antagonists.
7902375 5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as inhibitors of phosphatidylin ositol 3 kinase March 8, 2011
##STR00001## in free or salt form, wherein R.sup.a, R.sup.b, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that
7820694 Beta-2-adrenoreceptor agonists October 26, 2010
Compounds of formula ##STR00001## in free or salt or solvate form, where Ar is a group of formula ##STR00002## Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification,
7799810 Organic compounds September 21, 2010
The present invention concerns a compound of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, wherein the groups Ri- Rs are defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatid
7745462 Quinoline-2-one derivatives for the treatment of airways diseases June 29, 2010
Compounds of formula I ##STR00001## in free or salt form, wherein --C--Y--, R.sup.1 and R.sup.2 are G have the meanings as indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the .beta..sub.2-adrenoreceptor. Pharmaceut
7622483 .beta.2-adrenoceptor agonists November 24, 2009
Compounds of formula ##STR00001## in free or salt or solvate form, where Ar is a group of formula ##STR00002## Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification,
6878721 Beta2-adrenoceptor agonists April 12, 2005
Compounds of formula ##STR1##in free or salt or solvate form, where Ar is a group of formula ##STR2##Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification, their p










 
 
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