| Patent Number |
Title Of Patent |
Date Issued |
| 6060300 |
Thrombin muteins as antidotes for thrombin inhibitors |
May 9, 2000 |
| The invention concerns thrombin muteins which have the following differences in their sequences as compared with natural thrombin: (a) the exchange of a Gly after Ala, the Gly being in the sequence environment Tyr-Gly-Phe and having position 558 in natural human thrombin (SEQ ID No. |
| 5840722 |
Use of carboxylic acid derivatives as drugs |
November 24, 1998 |
| A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I ##STR1## |
| 5827731 |
Thrombin-inhibitory protein from ticks |
October 27, 1998 |
| A novel thrombin-inhibitory protein from ticks with a molecular weight of about 8000 Dalton and the N terminus Leu-Asn-Val-Leu-Cys-Asn-Asn-Pro-His-Thr-Ala-Asp-Cys-Asn-Asn-Asp-Ala-Gln-Va l-Asp is described. The protein is suitable for controlling diseases. |
| 5741674 |
Recombinant production of proteins in yeast |
April 21, 1998 |
| A process for the recombinant production of proteins in the yeast Hansenula comprises transforming Hansenula with an expression cassette which comprises the following structural elements encoded:whereL is a leader sequence,A is an adaptor producing an alpha-helix structure,P is a processing |
| 5672487 |
Recombinant production of proteins in yeast |
September 30, 1997 |
| A process for the recombinant production of proteins in yeast comprises transforming the yeast with an expression cassette which comprises the following structural elements encoded:whereL is a leader sequence of an animal peptide neurohormone,A is an adaptor producing an alpha-helix structur |
